Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Medical Imaging Technology》 2004-10
Add to Favorite Get Latest Update

Preliminary evaluation of fatty liver in rats by in vivo ~1H MR spectroscopy

FAN Ming-xia, TIAN Jian-ming, LU Jian-ping, JIN Ai-guo, ZENG Hao (Department of Radiology, Changhai Hospital, The Second Military Medical University, Shanghai 200433, China)  
Objective To study the usefulness of 1H MRS in fatty liver. Methods MR-chemical shift imaging (In phase sequence versus Out phase sequence) and 1H MRS using 2D chemical shift imaging SE sequence at 1.5 T were performed on 13 fatty rat livers (4 mild,3 moderate,6 severe) and 5 normal rat livers. Results There were no methylene spectrum at 1.25 ppm in normal livers, whereas the methylene (-CH 2)n measured spectrum fitted well with the theoretical spectrum at 0.89-1.31 ppm in 13 fatty livers. The mean spectra integral of (-CH 2)n increased with fat content: there was distinct difference between mild and severe fatty liver ( P 0.05), while the difference was not statistically significant between normal and mild fatty liver, as well as moderate and severe fatty liver ( P 0.05). The measurement of fatty content change of 1H MRS was similar with the decreased percentage of signal intensities on the Out phase sequence versus the In phase sequence of MR Imaging. There was a high correlation between 1H MRS and histology grade ( r =0.93, P =0.000). Conclusion It suggested that 1H MR spectroscopy using the technique of CSI SE is useful to detect and quantify fatty infiltration in liver.
【CateGory Index】: R445.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 10 Hits
1 YANG Ning-jing1,2,SONG Bin1,TANG He-han1,CHEN Guang-wen11Department of Radiology,West China Hospital of Sichuan University,Chengdu 610041,China; 2Sichuan Cancer Hospital,Chengdu 610041,China0;In vivo semiquantitative evaluation of liver fat content in alcoholic and nonalcoholic fatty liver rat models:comparison between dual-echo T1-weighted imaging and ~1H-MR spectroscopy with correlation of histopathology[J];Chinese Journal of Magnetic Resonance Imaging;2010-03
2 SU Zhong-zhen1, SHAN Hong1, HE Bing-jun1, LV Wen-tian1, MENG Xiao-chun1, WANG Jin1, ZHU Kang-shun1, YANG Yang2, CHEN Gui-hua2(1. Department of Radiology; 2. Department of Liver Transplantation, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China);Comparison on the values of STEAM and PRESS sequences in ~1H MRS quantitative evaluation of fatty liver[J];Chinese Journal of Interventional Imaging and Therapy;2008-02
3 YAN Ronghua, XIAO Enhua Department of Radiology, The Second Xiangya Hospital, Central south University, Changsha 410011,P.R.China;Comparison of STEAM and PRESS in vivo Two Dimension Multi voxel ~1H Magnetic Resonance Spectroscopy for Rabbit Liver VX2 Tumor[J];Journal of Clinical Radiology;2008-02
4 YAN Ronghua, XIAO Enhua, TANG Mi, et al.Department of Radiology, the Second Xiangya Hospital,Central-south University, Changsha, Hunan Province 410011,P.R.China;Dynamic Evaluation of in Vivo Two-dimensional Multi-voxel Hydrogen 1 Magnetic Resonance Spectroscopic Findings in the Rabbit VX2 Tumor Model Correlated with Pathology[J];Journal of Clinical Radiology;2008-04
5 Liu Zaiyi1,2,3 Liu Xiaoying2,3 Xu Li1,2,3 Li Yan1,2,3 Wang Qiushi1,2,3Zheng Junhui1,2,3 Liang Changhong1,2,3 1(Department of Radiology,Guangdong General Hospital,Guangzhou 510080,China)2(Guangdong Academy of Medical Sciences,Guangzhou 510080,China)3(Research Center of Medical Sciences,Guangdong General Hospital,Guangzhou 510080,China);Effects of Echo Time on the Liver Fat Quantification Using Proton Magnetic Resonance Spectroscopy[J];Journal of Biomedical Engineering;2010-04
6 Rong-Hua Yan En-Hua Xiao Bin Liang Department of Radiology,the Second Xiangya Hospital of Central South University,Changsha 410011,Hunan Province,China;Technology of in vivo twodimension multi-voxel 1~H magnetic resonance spectroscopy for rabbit liver VX2 tumor[J];World Chinese Journal of Digestology;2008-06
7 ZHAO Li-ming,YANG Ning-jing,SONG Bin. Department of Radiology,West China Hospital,Sichuan University,Chengdu 610041, China;Advances in Medical Imaging Evaluation of Fatty Liver[J];Chinese Journal of Bases and Clinics in General Surgery;2008-01
8 ZHAO Li-ming,SONG Bin,CHEN Guang-wen,YUAN Fang,HUANG Zi-xing,YANG Nin-jing.Department of Radiology,West China Hospital,Sichuan University,Chengdu 610041,China;Value of ~1H-MR Spectroscopy for Quantification of Hepatic Steatosis on 3.0 T MR System[J];Chinese Journal of Bases and Clinics in General Surgery;2010-01
9 BAI Liang-cai*, GUO Shun-lin, ZHOU Huai-qi, LEI Jun-qiang, DOU Yu, ZHANG Yi(Department of Radiology, the First Hospital of Lanzhou University, Lanzhou 730000, China);~1H MR spectroscopy in quantitative evaluation of fatty liver: pilot study[J];Chinese Journal of Medical Imaging Technology;2006-04
10 ZHANG Jing, CHENG Liu-quan, YE Hui-yi*, CAI You-quan, MA Lin, SUN Fei, GUO Xing-gao(Department of Radiology, PLA General Hospital, Beijing 100853, China);In vivo proton MR spectroscopy of normal liver on 3.0T MR scanner: quatitative analysis[J];Chinese Journal of Medical Imaging Technology;2007-08
【Citations】
Chinese Journal Full-text Database 1 Hits
1 Xu Haibo,Kong Xiangquan,Xiong Yin,et al.Department of Radiology Xiehe Hospital,Affiliated to Tongji Medical College of Huazhong University of Science & Techology,Wuhan 430022;Hepatic fatty infiltration:MR findings and choice of MR sequences[J];Radiologic Practice;2001-01
【Co-citations】
Chinese Journal Full-text Database 3 Hits
1 YANG Zhenghan, ZHENG Jianjun, ZHAO Weifeng,et al. Department of Radiology, Beijing Hospital, Beijing 100730, P. R. China[HJ5mm];Preliminary Clinical Application of Opposed Phase Imaging by Using Balance Steady State Free Precession in Diagnosis of Fat Containing Lesions in the Upper Abdomen[J];Journal of Clinical Radiology;2006-10
2 GUO Xing-hua*,LIU Qi-wang,WANG Juan-ping,ZHANG Chong-jie,ZHENG Guo-fang,FAN Rui-qiang,ZHU Su-mei.*Department of Medical Imaging,Shanxi Provincial Yuncheng Central Hospital,Yuncheng,044000,China;The contribution of chemical shift imaging with digital subtracting images to the diagnosis of steatohepatitis[J];Chinese Journal of Radiology;2006-11
3 ZHAO Li-ming1,2,SONG Bin1,CHEN Guang-wen2,YUAN Fang1.1.Department of Radiology,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China;2.Department of Radiology,Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital,Chengdu 610072,Sichuan Province,China;Comparative Study of Quantitative Diagnosis of Hepatic Fat Content by MRI and Patholgy[J];Chinese Journal of Bases and Clinics in General Surgery;2011-06
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Lin Guangwu Zhou Chunwu~# Department of Radiology,Cancer Hospital,CAMS & PUMC,Beijing 100021,China;The advancement of functional magnetic resonance imaging in tumor diagnosis and appreciation of curative effects of liver disease[J];Oncology Progress;2007-05
2 Zhang Zhaocheng Department of Pathology;STUDY OF HBsAg, HBcAg AND GLYCOGEN IN HUMAN HEPATOCELLULAR CARCINOMA[J];;1991-01
3 ;Advanced research on alcoholic liver disease[J];Journal of Jilin University(Medicine Edition);2006-04
4 Li Hanying,Yuan Lifang,Dong Changfeng,et al Department of Ultrasound,Shenzhen East Lake Hospital,Shenzhen 518020 China;Study on Fatty Liver Patients with Ultrasound Tissue Characterization[J];Chinese Journal of Ultrasound Diagnosis;2005-04
5 YUAN Zheng,XIAO Xiang-sheng,LIU Shi-yuan,SUN Zhi-chao,DONG Sheng,DONG Wei-hua,JIA Ning-yang,YAN Bing (Department of Radiology,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China);Clinical application of diffusion weighted MR imaging in follow-up of patients receiving transcatheter arterial chemoembolization for liver cancer[J];Academic Journal of Second Military Medical University;2007-09
6 JIAHong-shun,QUANXian-yue,ZENGSheng,WENZhi-bo Departmentof Radiology,ZhujiangHospital,Guangzhou510282,China;Dynamic evaluation of rabbit VX2hepatic carcinoma with CT and MRI[J];Journal of First Military Medical University;2002-02
7 XU Shao-bin1,QUAN Xian-yue2,SUN Xi-jie2 1Imaging Center,Pingzhou Hospital,Foshan 528251,China;2Imaging Center,Zhujiang Hospital,Southern Medical University,Guangzhou 510282,China;Preliminary quantitative study of dynamic magnetic resonance diffusion tensor imaging in rabbit models implanted with hepatic tumor grafts from VX2[J];Journal of Southern Medical University;2006-03
8 QUAN Xian-Yue1,ZHANG Xue-Lin2,SUN Xi-Jie1,Xing Hai-Fang3,LIANG Wen1 1Imaging Center,Zhujiang Hospital,Southern Medical University,Guangzhou 510282,China;2Diagnositic Imaging Center,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;3GE(China)Medical System,Guangzhou 510060,China;Quantitative study of dynamic magnetic resonance perfusion-weighted imaging in rabbit models of implanted hepatic VX2 tumor[J];Journal of Southern Medical University;2006-05
9 Xu Haibo,Kong Xiangquan,Xiong Yin,et al.Department of Radiology Xiehe Hospital,Affiliated to Tongji Medical College of Huazhong University of Science & Techology,Wuhan 430022;Hepatic fatty infiltration:MR findings and choice of MR sequences[J];Radiologic Practice;2001-01
10 ZHEN Jun-hui,LIANG Chang-hong,XIE Su-fei,et al.Department of Radiology,Guangdong Provincal People′s Hospital,Guangdong 510080,P.R.China;Study of the Factors Affecting the ~1H MR Spectroscopy Imaging of Fatty Liver.[J];Radiologic Practice;2005-09
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 Du-Jun Bian,En-Hua Xiao,Dong-Xu Hu,Xiang-Yu Chen,Wei-Jun Situ,Shu-Wen Yuan,Jian-Ling Sun,Li-Ping YangDepartment of Radiology,The Second Xiangya Hospital,Central South University,Changsha,Hunan 410011,P.R.China;Magnetic resonance spectroscopy on hepatocellular carcinoma after transcatheter arterial chemoembolization[J];Chinese Journal of Cancer;2010-02
2 WANG Nan,QI Jian-pin,DONG Hui,et al.Department of Radiology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,P.R.China;Application of Proton Magnetic Resonance Spectroscopy (~1H-MRS) and CT in the Diagnosis and Evaluation of Therapeutic Effects in Nonalcoholic Fatty Liver Disease (NAFLD)[J];Radiologic Practice;2007-12
3 WANG Yan-zhi,SONG Zhen-ya.Department of Gastroenterology,the Second Affiliated Hospital,Medical College of Zhejiang University,Hangzhou(310009),China;Research progress of magnetic resonance spectroscopy in liver diseases[J];International Journal of Digestive Diseases;2009-01
4 ;Diffusion tensor imaging:application in abdomen[J];International Journal of Medical Radiology;2011-03
5 YOU Ke-zeng,SHEN Zhi-wei,CAO Zhen,YANG Zhong-xian,CHENG Xiao-fang,YAO Jian-li,WU Ren-hua Department of Radiology,the Second Affiliated Hospital of Shantou University Medical College,Shantou 515041,China;Metabolic changes of liver cell apoptosis:an in vivo 1H magnetic resonance spectroscopy study[J];Chinese Journal of Magnetic Resonance Imaging;2011-04
6 CHEN Liang1,JIANG Xin-qing1,WEI Xin-hua1,LIANG Pei-zhi2,WU Mei1,XU Hong-gang1,WU Hong-zhen1,LI Jiang-min3(1.Department of Radiology,2.Department of Gastroenterology,3.Department of Equipment Maintenance,Guangzhou First Municipal People's Hospital,Guangzhou 510180,China);~1H-MRS in rabbit models of hepatic VX2 carcinoma after high intensity focused ultrasound treatment[J];Chinese Journal of Interventional Imaging and Therapy;2010-01
7 RAO Jingjing,CAO Sihai,WANG Nan,et al.Department of Radiography,the Affiliated Tongji Hospital of Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei Province 430030,P.R.China;The Application of Proton Magnetic Resonance Spectroscopy (~1H-MRS) in Nonalcoholic Fatty Liver Disease[J];Journal of Clinical Radiology;2008-10
8 CAO Kai-ming,HAO Nan-xin,WANG Wei,CHANG Shi-xin,WANG Yi-bin,ZONG Gen-lin(Department of Radiology,Shanghai East Hospital Affiliated to Tongji University,Shanghai 200120,China);In vivo proton MR spectroscopy of normal human kidney on 3.0T MR scanner[J];Journal of China Clinic Medical Imaging;2009-09
9 HUANG Rong,LIANG Zhuo-dong,SHAN Hui-ming,Tian Xing,Chen Peng,WENG De-he#,FENG Fei,LIU Peng-cheng*Radiology Department of Peking University Shenzhen Hospital,Shenzhen,China,518036#Siemens(Shenzhen) Magnetic Resonance Ltd.*Corresponding author;Application of A New Water-Fat Separation MR Technique in Hepatic Steatosis[J];Chinese Journal of Clinical Gastroenterology;2011-04
10 Liu Zaiyi1,2,3 Liu Xiaoying2,3 Xu Li1,2,3 Li Yan1,2,3 Wang Qiushi1,2,3Zheng Junhui1,2,3 Liang Changhong1,2,3 1(Department of Radiology,Guangdong General Hospital,Guangzhou 510080,China)2(Guangdong Academy of Medical Sciences,Guangzhou 510080,China)3(Research Center of Medical Sciences,Guangdong General Hospital,Guangzhou 510080,China);Effects of Echo Time on the Liver Fat Quantification Using Proton Magnetic Resonance Spectroscopy[J];Journal of Biomedical Engineering;2010-04
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Zhao Xinming, Wu Ning, Ouyang Han, et al. Department of Diagnostic Radiology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021;Imaging manifestations of tumors metastasized in fatty liver[J];CHINESE JOURNAL OF ONCOLOGY;1998-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved