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《Chinese Journal of Medical Imaging Technology》 2005-08
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Multi-slice CT perfusion imaging in diagnosis of cerebral neoplasms

WU Jian-lin~*, LI Zhi-yong, MIAO Yan-wei, NING Dian-xiu, WANG Ke-li, HAN Rui (Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China)  
Objective To assess the clinical application value of perfusion imaging with multi-slice helical CT (MSCT) in the diagnosis of cerebral neoplasms. Methods Thirty-four patients with brain neoplasms, including 10 cases with cerebral gliomas, 9 with brain metastases, 7 with meningiomas, 5 with pituitary neoplasms and 3 with recurrent neoplasms, underwent perfusion imaging by MSCT. The CT perfusion images were analyzed using perfusion software (GE). Results The mean CBF value and CBV value increased in cerebral neoplasms than in normal brain tissue. MTT value increased apparently in metastasis, while PS value increased apparently in all brain neoplasms. CBF value increased 2.5 times in recurrent neoplasms, reached 110 ml/(100 g·min). PS image was helpful to define the tumoral outline and find small tumor. Conclusion MSCT perfusion imaging plays an important role in revealing the brain neoplasms blood perfusion, in differential diagnosis of brain neoplasms, and in defining the tumoral margin and finding the recurrent tumors.
【CateGory Index】: R739.4
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