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《Chinese Journal of Medical Imaging Technology》 2008-03
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The optimization of contrast media injection protocol in heart coronary CTA by 64-MSCT

CUI Yan-hai,HUANG Mei-ping,LIANG Chang-hong,LUI Hui,ZHOU Tao,LUI Qi-shun(Department of Radiology,Guangdong Provincial People's Hospital,Guangzhou 510080,China)  
Objective To compare the enhancement of coronary arteries and the quality of reconstruction images using different contrast materials(CM) injection protocols on 64-multidetector computed tomography(64-MSCT) coronary angiography.Methods Fifty-eight patients were divided into three groups and underwent coronary artery CTA with three different injection protocols,respectively:group 1:300 mgI/m×5 ml/s,60-80 ml CM+50 ml saline,group 2:370 mgI/ml×4 ml/s,65-75 ml CM,group 3:370 mgI/ml×3 ml/s,65-75 ml CM.The enhancement of coronary arteries and the definition of the reconstructed vessels were evaluated,respectively.Results The mean degree of enhancement of coronary arteries were similar(about 350-370 HU) in group 1 and group 2.The difference between the two groups was insignificant.The mean degree of enhancement of coronary arteries in group 2(about 360 HU) was higher than that in group 3(about 330 HU).However,there was no significant difference between them.The quality of reconstruction images between group 2 and group 3 were equal,too.96.3% of images were adequate for diagnostic need.Conclusion The enhancement of coronary arteries is similar using different CM injection protocols with the same time-iodine loading dose of 370 mgI/ml×3 ml/s.The enhancement of 330 HU is competent for diagnosing coronary artery disease.
【Fund】: 广东省科技攻关项目(2006B36030026);; 广州省科技攻关项目(2006Z3-E0241)
【CateGory Index】: R816.2
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