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《Chinese Journal of Medical Imaging Technology》 2009-04
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Preliminary application of 3D CT whole brain perfused blood volume imaging in hyperacute cerebral infarction

ZHANG Miao,LU Jie,LI Kun-cheng,SUI Xin,CAO Yan-xiang(Department of Radiology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China)  
Objective To observe the diagnostic value of 3D CT whole brain perfused blood volume(PBV)in hyperacute cerebral infarction patients.Methods Conventional cerebral plain CT and CT angiography(CTA)were performed on 25 patients with hyperacute stroke within 6 h.3D PBV calculations were based on the CTA and the plain CT images covering the whole brain.The detection rate of ischemia on 3D PBV images was compared with the baseline plain CT.Follow-up CT examinations for the depiction of definite infarction were obtained at 2-7 d.The ischemic lesion volume on 3D PBV images was compared with the follow-up plain CT.Results Baseline plain CT demonstrated early ischemic signs in 12 of 25 patients.3D PBV demonstrated perfusion deficits corresponding to clinical symptoms in all the 25 patients.Moreover,statistical significant correlation was found between the ischemic lesion volume on 3D PBV and the follow-up infarct(Spearman's rs=0.837,P0.001).Conclusion In hyperacute cerebral infarction patients,3D PBV images from CTA source images and plain CT images can improve detection rate of ischemia by avoiding omission of lesions and assess the full extent of ischemia that correlating well with the follow-up infarct.
【CateGory Index】: R743.33
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