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《Chinese Journal of Medical Imaging Technology》 2009-S1
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An experimental study of different concentration contrast media in cerebral CT perfusion imaging of healthy rabbits

LIU Hong-jun,LIANG Chang-hong,WANG Guang-yi,HUANG Biao(Department of Radiology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510080,China)  
Objective To evaluate the effects of high-concentration contrast media(400 mgI/ml)with low flow rate on the cerebral CT perfusion imaging of healthy rabbits.Methods Twelve New Zealand white rabbits were randomly separated into three groups.They underwent cerebral CT perfusion imaging with protocol A(Iomeprol:400 mgI/ml,flow rate:1.0 ml/s),protocol B(Iomeprol:400 mgI/ml,flow rate:0.5 ml/s),protocol C(300 mgI/ml,flow rate:1.0 ml/s).The total iodine for each injection was 0.5 g/kg.CBFs,CBVs,MTTs,TTPs and CT values of middle cerebral artery of each protocol were acquired and compared statistically.Results The mean CBFs of three protocol were(69.8±11.4),(72.2±12.8),and(74.8±10.3)ml/(min·100 g)respectively(P=0.759).The mean CBVs of three protocol were(2.5±0.3)ml/100 g,(2.7±0.2)ml/100 g,(2.6±0.3)ml/100 g,respectively.The mean MTTs of three protocol were(2.27±0.19)s,(2.30±0.26)s,(2.55±0.30)s,respectively.The TTPs of three protocol were 4 s,5 s,5 s respectively.And mean CT value([193.5±5.1]HU)of middle cerebral artery at peak time was higher than that of protocol B([164.7±5.2]HU)and protocol C([163.0±7.1]HU),but the difference between protocol B and protocol C was not significant.Conclusion Cerebral CT perfusion imaging of healthy rabbits using high-concentration contrast media with low flow rate will not affect the perfusion parameters.Under same injection rate,high-concentration contrast media may improve the display of vessels.
【CateGory Index】: R816.1
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【Citations】
Chinese Journal Full-text Database 4 Hits
1 GAO Yong-an.Department of Radiology,Xuanwu Hospital,Capital University of Medical Sciences,Beijing 100053,China;Analysis of the advantages about 64-slice SCT in the diagnosis of nervous system diseases[J];Chinese Journal of Cenebrovascular Diseases;2005-11
2 JI Li-biao,WANG De-hang,LIU Sheng,SHI Hai-bin(Department of Radiology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China);An Experimental Study about Contrast Medium Injection Rate and Dose in Cerebral CT Perfusion Imaging[J];Journal of Practical Radiology;2005-10
3 LIANG Jianying~, GUO Xing, WANG Erniu, et al. ~Department of Radiology, Changzhi Medical University, Changzhi 046000,China;The preliminary study of CT perfusion methods in intra-axial ischemic disease[J];Chinese Journal of Radiology;2001-10
4 Zheng Jin,Jiang Anqiu,Wu Zhiyuan, Fu Jianxiong,Lin Jun,Chen Juan,Shi Binbin,Zhang Ping,Song Yuanyuan (Department of CT,Subei people's Hospital of Jiangsu Province,Yangzhou 225001);The Preliminary Study of Perfusion Imaging in Brain Tumor with Multislice Spiral CT[J];Chinese Journal of Medical Imaging;2005-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ;Comparison of value between 16 slice CTA and 3D-DSA in diagnosis of intracranial very small aneurysm[J];Journal of Jilin University(Medicine Edition);2007-04
2 TONG Dan,HUA Shu-cheng,WANG Da-wei,et al;Analysis of image quantity of CTA and 3D-DSA in detection of aneurysm[J];Journal of Jilin University(Medicine Edition);2008-02
3 DAI Weiying,JIN Song,TIAN Chao,YAN Shixin. Department of Radiology, Tianjin Huanhu Hospital, Tianjin 300060, China;The clinical application of 64-slice spiral CT angiography in carotid artery bifurcation disease[J];International Journal of Medical Radiology;2008-06
4 WANG Hong-shenga,ZHAO Pei-lina,WANG Li-lia,L Xiao-chenga,LIU Hong-quana,YIN Shang-jionga,L Guo-shib,WANG De-renb(a.Department of Neurosurgery;b.CT Center,the 251st Hospital of PLA,Zhangjiakou,Hebei 075000,China);Application of 64-Row Spiral CT Angiography in the Clipping and Coiling of Intracranial Aneurysms[J];Medical Journal of National Defending Forces in North China;2009-01
5 XIE An-Ming,LI Gong-Jie(Department of Radiology,Affiliated Hospital,Academy of Military Medical Sciences,Beijing 100071,China);Progress in study on brain perfusion imaging of moyamoya disease[J];Bulletin of the Academy of Military Medical Sciences;2009-03
6 LIU Hualiang,GAO Yongan Department of Radiology,Xuanwu Hospital,Capital University of Medical Sciences,Beijing 100053,P.R.China;The Comparative Study of CT and TCD on Calcification of Middle Cerebral Artery[J];Journal of Clinical Radiology;2007-04
7 ZHANG Tonghua,HU Chunhong,WU Qingde,et al.Center of Medical Imaging,The First Affiliated Hospital of Suzhou University,Suzhou,Jiangsu Province 215006,P.R.China;The Difference between rCBF and rCBV of Astrocytomas and Its Clinical Significance[J];Journal of Clinical Radiology;2007-06
8 LIU Hua-liang,GAO Yong-an.Department of Radiology,Xuanwu Hospital,Capital University of Medical Sciences,Beijing 100053,China;The relationship between middle cerebral artery calcification and cerebral infarction: a contrast analysis by CT scanning[J];Chinese Journal of Cerebrovascular Diseases;2006-04
9 WANG Hong-sheng,ZHAO Pei-lin,SUN Xiao-feng,LIU Hong-quan,YIN Shang-jiong,Lv Guo-shi,ZUO Hong,WANG De-ren.Department of Neurosurgery,the 251st Hospital of PLA,Zhangjiakou 075000,China;Diagnosis of intracranial aneurysm with 64-slice spiral CT angiography[J];Chinese Journal of Cerebrovascular Diseases;2007-02
10 WANG Hong-sheng,ZHAO Pei-lin,WANG Li-li,LIU Hong-quan,YIN Shang-jiong,L ü Guo-shi.Department of Neurosurgery,the 251st Hospital of PLA,Zhangjiakou 075000,China;Guiding value of 64-slice helical CT angiography in intracranial aneurysm surgery[J];Chinese Journal of Cerebrovascular Diseases;2008-11
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 ;Symposium on the Progress and Strategy of Digitalization of Traditional X-Ray Examination and PACS[J];China Comtemporary Medicine;2001-03
2 WU Lianghao,GUO Hanqiang,GUAN Wei,et al.Department of Radiology,Zhejiang Hospital,Hangzhou 310013;Application of volume rendering and shaded surface display in CT angiography of vertebral artery[J];Radiologic Practice;2002-06
3 LI Zhiyong,WU Jianlin,NING Dianxiu,et al.Department of Radiology,the First Affiliated Hospital,Dalian Medical University,Liaoning 116011;Preliminary application of perfusion imaging in neoplasms in the brain and body with multislice helical CT[J];Radiologic Practice;2003-04
4 Gong Jianping; Yang Xiaochun; Lu Zhian; et al (Department of Radiology ,2nd AffliatedHospital, Suzhou Medical College, Suzhou 215004);The Effect of Osseous Hypertrophy of Cervical Luschka's Joints on Vertebral Artery[J];JOURNAL OF CLINICAL RADILOLGY;1998-06
5 GAO Yongan, JI Renzhen, GU Yebing, et al. Department of Radiology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, P. R. China;Clinical Application of Spiral CT Scanning in the Diagnosis of Cerebral Venous Thrombosis[J];Journal of Clinical Radiololgy;2003-06
6 CHEN Xiangmin, XU Haibin, MA Hongchun,et al. Department of Radiology, Qingdao People's Hospital, Qingdao, Shandong Province 266001, P. R. China;The Application of Multi-Slice CT Aingiography in Etiology Diagnosis of Vertebrobasilar Insufficiency[J];Journal of Clinical Radiololgy;2005-09
7 HUANG Biao, LIANG Chang-hong, ZHANG Yun-ting, ZHOU Dong, LIN Hua-huan, RU Guang-teng, LIU Hong-jun, LIU Qi-shun(Department of Radiology, Guangdong Provincial People’s Hospital, Guangzhou 510080,China);The Correlative Study Between CT Perfusion Imaging and Microvascular Density of Astrocytoma[J];Journal of Practical Radiology;2005-05
8 LIANG Jianying~, GUO Xing, WANG Erniu, et al. ~Department of Radiology, Changzhi Medical University, Changzhi 046000,China;The preliminary study of CT perfusion methods in intra-axial ischemic disease[J];Chinese Journal of Radiology;2001-10
9 ZHAO Hong,ZHOU Kang-rong,YAN Fu-hua. Department of Radiology Zho ngshan Hospital,Fudan University,Shanghai 200032,China Corresponding author: ZHAO Hong,519000,Department of Radiology,the Fifth Affili ated Hospital of Sun Yat-Sen University,Zhuhai;Effect of contrast medium injection rate on hepatic circulatory time by using hepatic multirow-detector helical CT scanner[J];Chinese Journal of Radiology;2004-01
10 CHEN Juan *, LIU Yin-hong, ZHAO Bin, ZHOU Cheng, YANG Zheng-han. *Department of Radiology, Beijing Hospital, Ministry of Health of the People′s Republic of China, Beijing 100730, China;Study on the relationship among multi-slice CT perfusion and National Institutes of Health Stroke Scale Score and clinical outcome in patients at hyperacute stroke[J];Chinese Journal of Radiology;2005-04
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