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《Chinese Journal of Medical Imaging Technology》 2015-03
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Spectral CT imaging in diagnosis of benign and malignant parotid tumors

JIN Xiao-yuan;LIU Bin;LI Hong-wen;WU Xing-wang;WANG Jie;Department of Radiology,the First Affiliated Hospital of Anhui Medical University;  
Objective To investigate the value of gemstone spectral imaging(GSI)in diagnosis of benign and malignant parotid tumors.Methods Totally of 62 patients with parotid tumors confirmed by surgery and pathology,including 50 with benign tumors and 12 with malignant tumors were enrolled.All the patients examined with spectral CT scanning.Iodine concentration,slope of spectral curve,effective-Z were obtained by using GSI Viewer software.Wilcoxon rank sum test were used to analyze the differences of parameters between the benign and malignant parotid tumors.ROC curve was drawn to get the best diagnostic threshold and diagnostic sensitivity and specificity.Results In non-contrast CT imaging,the median and quartile range of iodine concentration,slope of spectral curve,effective-Z were-1.41×100μg/ml(-2.25×100μg/ml,0.16×100μg/ml),-0.10(-0.31,0.12),7.25(7.17,7.40)in benign tumors,-1.13×100μg/ml(-1.46×100μg/ml,1.44×100μg/ml),1.01(-0.19,2.04),7.17(7.13,7.48)in malignant tumors.There were no significant difference(all P0.05).In the arterial phase,the median and quartile range of iodine concentration,slope of spectral curve effective-Z were 9.65×100μg/ml(4.29×100μg/ml,18.37×100μg/ml),0.69(0.31,1.59),7.89(7.71,9.15)in benign tumors,18.04×100μg/ml(12.50×100μg/ml,20.98×100μg/ml),1.56(1.29,2.65),9.22(9.11,9.28)in malignant tumors(Zvalue were-3.273,-2.43,-3.01,respectively,all P 0.05).In venous phase,no significant difference were found for each parameter between the two groups(all P0.05).In the arterial phase,taking iodine concentration18.90μg/ml,slope of spectral curve1.247,effective-Z9.05 as threshold to predict malignancy,the sensitivity and specificity were 91.7%,75.0%,91.7% and 79.5%,71.8%,82.1%,respectively.Conclusion Spectral CT imaging have a potential value in differential diagnosis of benign and malignant parotid tumors.
【CateGory Index】: R739.8;R730.44
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