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《Chinese Journal of Birth Health & Heredity》 2009-08
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Analysis of the factors affecting abnormal fertilization on in vitro fertilization

XU Fen,XU Wang-ming,XIE Qing-zhen.(Reproductive Medical Center of Renmin Hospital,Wuhan University,Wuhan 430060)  
Objective:To investigate the factors affecting monopronuclear and polypronuclear in in vitro fertilization.Methods:The 6815 fertilized ovum of 9718 oocytes from 608 IVF cycles and 319 ICSI cycles were analyzed by analysis of variance to show the influence of the age of women,the stimulating protocol,serum estradiol level on day of hCG,the number of retrieved oocytes on the incidence of monopronuclear and polypronuclear.Results:(1) The age of women,the stimulating protocol,serum estradiol level on day of hCG,the number of retrieved oocytes have no significant influence on the incidence of monopronuclear.(2)In IVF group,the incidence of polypronuclear is higher than that in ICSI group,but total fertility rate was inferior to the latter.And the incidence of polypronuclear is significantly increased when retrieved oocytes are more than 15 or serum estradiol level on day of hCG is more than 4000 pg/ml.(3)In ICSI group,the incidence of polypronuclear is significantly increased when the age of female is older than 30 years old.Conclusion:The affecting factors and incidence mechanism are different between IVF and ICSI,make sure that every couple of infertility have optimal modality in vitro fertilization will help to decline the incidence of monopronuclear and polypronuclear.
【CateGory Index】: R714.8
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1 YAN Jun-hao,CHEN Zi-jiang,LI Yuan,HU Jing-mei,GAO Shan-shan(Reproductive Medical Center,Shandong Provincial Hospital,Shandong University,Jinan 250021,Shandong,China);Sex chromosome analysis of embryos from monopronucleus zygotes derived from in-vitro fertilization and intracytoplasmic sperm injection in human[J];Journal of Shandong University(Health Sciences);2006-06
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1 ZHANG Zhou1, 2, SHI Juan-zi2, ZHOU Han-ying2 , QIANG rong2 1.Xi'an Jiaotong university school of medicine,Xian 710061 China;2. Maternal and child health hospital of Shaanxi province, Xian 710003 China;Chromosomal karyotypes analysis on patients with severe oligospermia and azoospermia[J];Gansu Medical Journal;2009-01
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Chinese Journal Full-text Database 1 Hits
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