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《Pharmacology and Clinics of Chinese Materia Medica》 1992-03
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EFFECTS OF HEAT-CLEARING HERBS AND YIN-NOURISHING HERBS ON GASTROITESTINAL MOTILITY

Chen Yong (Institute of Viscera-Stale and liver Diseases, Hubei College of Traditional Chinese Medicine, Wuhan 430061)  
The effects of Heat-clearing herbs and Yin-nourishing herbs on gastrointestinal motility in experimental animals were observed. The results were as follows: (1) Heat-clearing harbs and Yin-nourishing herbs could inhibit the gastrointestinal propulsion in the mice and antagonise the hyperactivity of gastrointestinal propulsion induced by neostigmine in the mice; (2) Heat-clearing herbs and Yin-nourishing herbs could inhibit the automatic activity of isolated intestine of rabbit and antagonise the spasmodic activity of isolated intestine of rabbit induced by actylcholine or barium chlorid. It is concluded that Heat-clearing herbs and Yin-nourishing herbs inhibit gastrointestinal motility by means of antagonising actylcholine and directly relaxing the smooth muscles of gastrointestinal tract.
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