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《Pharmacology and Clinics of Chinese Materia Medica》 2001-04
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Study on Antibacterical and Antipyretic Effect of Niuhuang Jiedu Tablet (Realger Free)

Yang Shiyou, Pei Yuemei, Liang Qiyong, et al. (Anhui Institute of Pharmacy Hefei 230022)  
Niuhuang Jiedu Tablet (Realger Free) has significant antibacterical effect. Bacteriostatic test in vitro show that this drug is most sensetive to Staphelococcus aureus and A streptococcus, and MIC is 7.8 and 15.6 mg/ml respectively. In vivo test show that ig 1.7 and 0.8g/kg of this drug the mice significantly decrease the mortality rate of the mice influenced by B streptococcus. This drug also show antipyretic effect, inhibiting the rise of body temperarure of rabbits and rats induced by cholera bacteria or 2,4 dinitrophenol. These effects are all same as that of Niuhuang Jiedu Tablet.
【Fund】: 国家新药研究基金资助项目 ;合同号 (94 95 34)
【CateGory Index】: R285.5
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