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《Pharmacology and Clinics of Chinese Materia Medica》 2003-03
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Experimental study on the anti-tumor effect of polysaccharide from Litsea pungens Hemsl Root (木姜子根多糖)

Ni Feng,Zhou Chunquan, Qiu songping, et al (Fujian Institute of TCM&Pharmacy, Fuzhou 350003,Fujian College of TCM)  
Objective: To study the activity of anti tumor of from Litsea pungens Hemsl Root (木姜子根多糖,MDT) in vivo and its direct effect on tumorous cells in vitro. Methods: The suspension of U 14 cells were inoculated to subaxillary of mice to observe the antineoplastic effect of MDT; The exclusion of trypan blue and MTT methods were used in this test to observe the direct influence of MDT and MDT bearing serum on growth of HL60?ECV 304?PC 3 and Lncap cells. Results: The MDT could inhibit the growth of tumor and clearly enhance the effect of anti cancer of CTX; it has some direct repression on HL60 cells, but the same effect of MDT bearing serum were not found. Conclusion: The MDT has an effect of anti tumor.
【CateGory Index】: R273
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