Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Pharmacology and Clinics of Chinese Materia Medica》 2015-02
Add to Favorite Get Latest Update

Ziqi water extract attenuates acute lung injury induced by lipopolysaccharide in mice

Zhang Tianzhu;Yang Shihai;Zhao Lei;Zhang Jinglong;Changchun University of Chinese Medicine;Jilin Agricultural University;  
Objective: To determine the protective effect of Ziqi water extract on acute lung injury induced by lipopolysaccharide(LPS).Methods:The BABL/C mice were randomly allocated into control,LPS,dexamethasone(2mg/kg),Ziqi water extract(4g/kg),and Ziqi water extract(8g/kg).The bronchoalveolar lavage fluid(BALF) samples were analyzed for the concentration of numbers of neutrophilic,SOD,MDA,NO,prostaglandin E2(PGE2),interleukin-6(IL-6) and tumor necrosis factor alpha(TNF-α),and the lung samples were taken for histologic evaluation and for determination of wet-to-dry(W/D) lung weight,The protein levels of cyclooxygenase-2(COX-2) were detected by Western blot analysis.Results: Pretreatment with Ziqi water extract prior to the administration of intratracheal LPS significantly induced a decrease in lung wet weight/dry weight ratio,in total leukocyte number and neutrophil percent in the BALF,and in PGE2 of lung in dose-dependent manners,and in IL-6,the tumor neurosis factor-α(TNF-α) in the BALF and COX-2 protein in lung.These results showed that anti-inflammatory effects of Ziqi water extract against the LPS-induced ALI.
【Fund】: 吉林省科学技术厅科技引导计划项目(200905110)
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 5 Hits
1 Mu Lisha;Cui Wen;Fei Ye;Fu Shenzhen;Wang Jing;Gao Zengping;School of Chinese Meteria Medica,Beijing University of Chinese Medicine;;Study on the Effective Component of Japanese Flowering Fern Rhizome with Anti-inflammatory Action[J];世界中医药;2014-03
2 LI Feng-xia1,WANG Dan1,HU Yuan-qing2,ZHANG Zhong3(1.Coll of Food and Drug,Anhui Sci and Tech Univ,Fengyang 233100,China; 2.Coll of Anim Sci and Tech,Anhui Sci and Tech Univ,Fengyang 233100,China; 3.Coll of Chem and Life Sci,Guangdong Univ of Petro Tech,Maoming 525000,China);Analysis of antioxidant activity of the Osmunda japonia flavonoids in vitro[J];扬州大学学报(农业与生命科学版);2011-04
3 LIANG Yun-jiang1,LI Wei1,WANG Wei-na1,LU Yu-han1,HE Zhong2 (1.Agricultural College of Yanbian University,Longjing 133400,China;2.Station for Popularizing Agricultural Technique of Wangqing County,Wangqing 133200,China);Biological Characteristics and Artificial Propagation on Osmunda japonica[J];北华大学学报(自然科学版);2010-02
4 LI Feng-xia,WANG Qing,ZHANG Zhong et al(Anhui Science and Technology University,Fengyang 233100,China);Extraction of Flavonoids of Osmunda Cinnamomea L Var.and a Study on Antioxidant of It[J];包装与食品机械;2008-01
5 ZHANG Qiujin , SHEN Hong, ZHANG Wei, LI Yinping, LI Tanshi. EmergencyDepartment, General Hospital of PLA, Beijing 100853, China;Effects of combined naloxone and methylprednisolone on nuclear factor-κB expression in the lung in acute lung injury in rats[J];中国危重病急救医学;2005-06
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Cheng Yumei;Yang Zhou;Shen Feng;Liu Bo;Wang Yahui;Wu Yanqi;Yao Ling;Liu Yuqing;Department of Intensive Care Unit,Affiliated Hospital of Guizhou Medical University;Department of Anesthesiology,Center Hospital of Xiangyang;Department of Intensive Care Unit,Second Affiliated Hospital of Guizhou Medical University;Department of Intensive Care Unit,Zhenjiang Fourth People's Hospital;;Comparison of lung protection for hydrochloric acid or oleic acid induced rat acute respiratory distress syndrome models pretreated with penehyclidine[J];中华危重病急救医学;2018-05
2 ZHAO Jie;WANG Bin-Qi;JIA Xiao;TONG Yi-Qin;HE Yi-Fa;GE Tai-Ming;Hubei Key Laboratory of Wetland Evolution and Ecological Restoration,China University of Geosciences;School of Forestry and Horticulture,Hubei University for Nationalities;;Development of SSR Markers to Assess Genetic Diversity in Osmunda japonica Thunb.[J];植物科学学报;2015-06
3 Wu Jinfu;Ge Shenghui;Jiang Lihua;Yang Xi;Wang Lijuan;Department of Anesthesiology,Third Affiliated Hospital of Zhengzhou University;Editorial Departement of Chinese Journal of Anesthesiology,Hebei Provincial Institute of Medical Science Information;;Effect of alprostadil on acute lung injury in septic rats[J];中华麻醉学杂志;2015-12
4 XIE Xiuhong;LI Wei;LI Cuilan;LIANG Yunjiang;College of Landscape Architecture,Changchun University;College of Agriculture,Yanbian University;College of Resource and Environmental Science,Jilin Agricultural University;;Spore Propagation Techniques of Osmunda cinnamomea L.var.asiatica[J];北方园艺;2015-20
5 Zhang Hui;Yu Peng;Zhang Nan;Liu Weiqiao;Wang Yao;Changchun University of Chinese Medicine;;Acteoside attenuates acute lung injury induced by lipopolysaccharide in mice[J];中药药理与临床;2015-03
6 Zhang Tianzhu;Yang Shihai;Zhao Lei;Zhang Jinglong;Changchun University of Chinese Medicine;Jilin Agricultural University;;Ziqi water extract attenuates acute lung injury induced by lipopolysaccharide in mice[J];中药药理与临床;2015-02
7 HE Wen-jing;ZHENG Wei;ZHOU Chang-hui;ZHANG Xu-hua;XING Dan-ying;XU Jian-long;YUAN Zhi-hua;LIU Huan;School of Agriculture, Yangtze University;Institute of Agricultural Economy and Technology Research, Hubei Academy of Agricultural Science;Hubei Changyou Modern Agriculture Incorporated Company;Institute of Crop Sciences, Chinese Academy of Agricultural Sciences;;Preliminary Studies on the Effects of Selenium Ore Powder on the Enrichment of Selenium Content in Osmunda japonica Thunb.[J];湖北农业科学;2015-03
8 Zhang Bin;Yao Yongxiu;Peng Yuhong;Yuan Ye;Department of Pharmacy & Laboratory,Ya'an Vacational College;;Evodiamine attenuates acute lung injury induced by lipopolysaccharide in mice[J];中药药理与临床;2014-06
9 ZHANG Tian-zhu;ZHANG Jing-long;HAO Bin-bin;XU Jiang;Changchun University of Chinese Medicine;;Lycium chinense Water Extract Attenuates Acute Lung Injury Induced by Lipopolysaccharide in Mice[J];中国实验方剂学杂志;2014-22
10 GUO Feng-ling;LI Jun-li;WANG Yun-qiang;WU Jin-ping;QIU Zheng-ming;Industrial Crops Institute of Hubei Academy of Agricultural Sciences;Wuhan University of Technology School of Science;;Optimizing conditions of Extracting Polyphenol from Osmunda cinnamomea L.var. asiatica[J];湖北农业科学;2014-21
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 LIANG Yun-jiang1,LI Wei1,WANG Wei-na1,LU Yu-han1,HE Zhong2 (1.Agricultural College of Yanbian University,Longjing 133400,China;2.Station for Popularizing Agricultural Technique of Wangqing County,Wangqing 133200,China);Biological Characteristics and Artificial Propagation on Osmunda japonica[J];北华大学学报(自然科学版);2010-02
2 CHEN Hongmei,WEI Benmei,ZHANG Zhiyong (Department of Chemical and Environmental Engineering,Wuhan Polytechnic University,Wuhan 430023,China);Microwave extraction technique and anti-oxidation activity of total flavonoid from Xinjiang apocynum venetum leaves[J];中国酿造;2010-01
3 Liu Jincheng,et al Harbin Medical University Daqing Branch(Daqing 163319);Pharmacological Research on Guanzhong[J];黑龙江医药;2008-04
4 LI Feng-xia,WANG Qing,ZHANG Zhong et al(Anhui Science and Technology University,Fengyang 233100,China);Extraction of Flavonoids of Osmunda Cinnamomea L Var.and a Study on Antioxidant of It[J];包装与食品机械;2008-01
5 JIAO Shi-rong(School of Bioengineering of Xihua University,Chengdu 610039 China),WANG Ling,et al.;Study on Flavonoids Extracted from Citrus Reticulate Peel by MAE and Its Antioxidant Activity[J];西华大学学报(自然科学版);2007-04
6 CHEN Xu-dan, YU Xiao-ying, HAO Xiao-meng, LU Xi, WANG Wei(College of Chemistry and Biology, Tianjin Normal University,Tianjin 300074,China);THE STUDY OF MANY FLAVONOIDS IN ANTI- FREE RADICALS[J];食品研究与开发;2007-06
7 LANG Na, LUO Hong-xia (Tianjin Jinghai Product Quality Supervision and Inspection Institute, Tianjin 301600, China);STUDY FOR THE ACTIVITY OF FLAVONOID IN HEMEROCALLIA FULVA[J];食品研究与开发;2007-03
8 WANG Mou-qiang,ZHANG Zhao-jun(Guizhou Institute of Horticulture,Guiyang 550006,China);Research Current Situation of Osmunda japonica and Its Development Countermeasures in the Southern Part of China[J];贵州农业科学;2006-04
9 HUANG Qiong, YANG Xing-fen, LI Wen-li, LI Zhi,HUANG Jun-ming, YANG Guo-guang, HUANG Jian-kang, ZHANG Bo (Guangdong Provincial Center for Disease Prevention and Control, Gunagdong Gunag zhou 510300, China);Study on anti-senescence and anti-oxidation effects of soybean isoflavones in rats[J];中国食品卫生杂志;2005-05
10 YOU Jian-ming (Department of Bioengineering,Sichuan Institute of Technology,Zigong 643000);Study on Comparing of Extractive Means of Flavonoinds from Zingiber officinalis[J];四川食品与发酵;2005-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved