Studies on antipyretic mechanism of clearingheat herbs:interfere with content of cAMP in rat hypothalamus
Xu Gang, Zhang Bing(Department of pharmacology of Guangzhou Medical College, PLA. Guangzhou 510315)
? We selected typical clearingherbs Scutellaria Rool, Honeysuckle Flower and Forsythia Fruit to form clearingheat prescription, probed in its antipyretic mechanism on temperature regulation center. The experimental results shows that affecting metabolism of febrile central medium cAMP, reducing its content and suppressing going up of temperature regulation point is one of antipyretic mechanism of clearingheat herbs.