Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Clinical Emergency》 2014-02
Add to Favorite Get Latest Update

Influence of nitric oxide by Qingfeitang on nitric oxide in exhaled breath condensate and serum of patients with ALI/ARDS

GU Yan;CHEN Jianrong;SHAO Feng;GAO Xiang;TANG Yanfen;XU Zhihua;LI Hong;Department of Emergency,Second Affiliated Hospital of Nantong University;Chinese Traditional Hospital of Nantong;  
Objective:To observe the changes of nitric oxide(NO)in exhaled breath condensate(EBC)and serum of patients with acute lung injury/acute respiratory distress syndrome(ALI/ARDS)during the treatment of Qingfeitang.Method:The study included 54mechanical ventilation patients with ALI/ARDS in ICU,all the patients were randomly divided into Qingfeitang treatment group and control group.The EBC were collected by improved EcoScreen condenser,in the first day and the fifth day after the diagnosis of ALI/ARDS,with the synchronous collection of the venous blood.The levels of NO in the EBC and serum were measured by EIA.At the same time record APACHEⅡscore,oxygenation index and the duration of mechanical ventilation.Result:①After treatment,The levels of EBC-NO and blood serum-NO(26.71±9.32μmol/L,31.28±8.73μmol/L)in Qingfeitang treatment group were significantly lower than in the control group(34.27±9.96μmol/L,39.34±9.15μmol/L). ②The oxygenation index in the two groups were all both increased.But the D-value of oxygenation index of the Qingfeitang treatment group(94.74±42.19)mmHg was significantly higher,compared with the control group(68.41±35.21)mmHg.③The duration of mechanical ventilation(225.06±74.79h)of the Qingfeitang treatment group was significantly less shorter than that of the control group(296.42±96.25h).④After treatment,the APACHEⅡscore(9.75±4.52)of the Qingfeitang treatment group was significantly lower than that of the control group(13.02±5.31).Conclusion:Qingfeitang could be an effective method complementary medicine for alleviating acute lung injury.
【Fund】: 江苏省中医药局科技项目(No:LZ11157);; 2012年南通市第四期“226工程”培养对象科研项目通委组发[2012]153号
【CateGory Index】: R563.8
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved