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Effect of Single and Coupled Chinese Drugs on Hemopoietic Cells-CFU-D

Ma Rou Xie Renfu Liao Junxian China-Japan Friendship Hospital,Beijing  
Twelve pairs of drugs which are the main components of Datusizi yin(Major Dodder Seed Decoction) and Shisiwei Jianzhong Tang(Decoction with 14 Ingredients to Reinforce Middle Jiao)have been proved clinically effective in treating aplastic anemia.The drugs are paired according to their properties known in the traditional Chinese medicine,and tested for their effect on the granulocytic progenitors CFU-D with diffusion chamber technique.Six pairs of them were shown to be able to promote proliferation of CFU-D. CFU-D growth could be enhanced by 9 of the 12 drugs of the 6 pairs when they were further assayed separatedly.The majority of the 6 pairs or 9 single drugs have the property of tonifying the kidney.The results of our observation further support the belief that kidney tonics are effective in treating aplastic anemia.
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