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Comparison of the Effects of Tonifying Kidney and Invigorating Spleen Regimen in Delaying Aging Changes

Shen Ziyin Hu Guorang The Institute of Integration of TCM and WM,Shanghai Medical University,Shanghai  
Both the prescriptions of tonifying Kidney and invigorating Spleen were highly praised among all the aging delaying prescriptions in TCM,but it was conflicting viewed by different schools that which regimen was the better one.For answering this question,90 healthy elder subjects were selected and were divided into three groups at random:(1)treated with tonifying Kidney regimen(TKR),(2)treated with invigorating Spleen regimen(ISR),and(3)controls.Before and after the treatment,their neuroendocrine and immune functions were simultaneously measured.The results showed that the activity of NK cell in the elderly group was higher than that in the youngsters and it could be further increased after the treatment in all these cases but the controls,which suggested that TKR and ISR had the effect of improving the nonspecific immune function.Early in 1984,TKR could improve the aging changes of the function of the hypothalamus- pituitary-testes axis was found.It raised the serum testosterone level and increased the response ability of pituitary to the stimulation of LH-RH.These effects were not observed in the control and ISR groups.In this article,the levels of serum LH and plasma cortisol were increased markedly in TKR group while the LH level was slightly increased and the cortisol level remained unchanged in ISR group were observed.All these data suggested that the effects of TKR were more significant and wider in application in delaying aging changes than that of ISR.
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