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《Chinese Journal of Integrated Traditional and Western Medicine》 1999-12
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Immunoregulation of Youguiyin, Sijunzitang, Taohong Siwutang in Treating Patients with Deficiency of Kidney, Spleen and Blood Stasis Syndrome

Xu Desheng, Shen Ziyin, Wang Wenjian, et al Visceral Picture Research Department, Huashan Hospital, Shanghai Medical University, Shanghai (200040)  
Objective: To study the different immunoregulatory effects of Youguiyin, Sijunzitang, Taohong Siwutang to patients with deficiency of Kidney, Spleen and blood stasis Syndrome respectively. Methods: The treated group, 40 patients in each with deficiency of Kidney, Spleen and blood stasis were treated with Youguiyin, Sijunzitang and Taohong Siwutang respectively. Three control groups (20 patients each) were established respectively. Peripheral venous level of complement C 3, circulating immunocomplex (CIC), interleukin 2 (IL 2), interferon γ (IFN γ), lymphocyte transformation rate (LTR), the activity of natural killer (NK) cell, and the phagocytic function of neutrophil were measured before and after treatment. Results: Sijunzitang could reduce the level of CIC (P0 01), raise the activity of NK cell and LRT (P0 01) of the patients with deficiency of Spleen syndrome; the same did the Youguiyin to that of patients with deficiency of Kidney syndrome. Also, Sijunzitang could increase the level of IL 2 in blood and the phagocytic function of neutrophil (P0 05); the Taohong Siwutang could lower the level of CIC to patients with blood stasis syndrome (P0 01), increase the activity of NK cells (P0 05). Conclusion: Youguiyin, Sijunzitang could enhance the immunoregulatory function of the patients with deficiency of Spleen and Kidney, particularly the cellular immune functions, in which the Sijunzitang effect is more complete and significant, while Taohong Siwutang eliminated the effect of CIC in blood better.
【Fund】: 国家自然科学基金!No .392 30 370
【CateGory Index】: R285
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