Study on the Separation, Cryopreservation and Recovery of Cord Blood Hematopoietic Stem/Progenitor Cells
Chen Junda Cai Haibo Tan Wensong Yu Juntang (East China University of Science and Technology Shanghai 200237)
Cord blood, as a new resource of hematopoeitic stem/progenitor cells, has a enrichment of CD34 + cells. The advantages of cord blood hematopoeitic stem cells are high speed proliferation, rich concentration and safety collection. Cord blood transplantation also has expected advantages such as safety, high efficiency and low expense. With the clinical success of cord blood transplantation, large scale cord blood bands are being built in many advanced countries in Europe and North America to meet the clinical application. The key technology of cord blood bank building for the ideal recovery of stem/progenitor cells includes improvement of cell cryopreservation prevention combination, cryopreservation rate control and cell recovery method. Cord blood separation and volume reduction is first needed to meet thd practical bank requirement for the high expense of liquid nitrogen preservation equipment.
【CateGory Index】： Q274