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《Journal of Anhui Normal University(Natural Science)》 2003-01
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A NOVEL SYNTHESIS OF ISOXAZOLES AND ISOXAZOLINES

SHANG Yong jia 1,\ LIU Hong mei 2 (1.College of Chemistry and Matierial Science, Anhui Normal University, Wuhu 241000, China;2. Nanjing Dongfang Chemical and Technologic Limited Company, Nanjing 210000, China)  
Isoxazoles and isoxazolines are versatile synthetic intermediates. A facile and novel synthesis of isoxazoles and isoxazolines through a 1,3-dipolar cycloaddition is described. Propargyl alcohol and allyl alcohol react with nitrile oxides generated in situ to give isoxazoles in good yield.
【Fund】: 安徽省教育厅基金 2 0 0 2KJ114
【CateGory Index】: O626
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