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《Journal of Anhui Traditional Chinese Medical College》 1989-03
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Effects of Total Alkaloids from Eupolyphage Sinensis Walk on the Pump Function of Rabbits Heart

Long Zijiang  
The experimental results demonstrated that in anesthized rabbits, total alkaloids from Eupolyphaga sinensis walk ( ESWA) used respectively 5 mg/kg, 10mg/kg, 15mg/kg, and 20mg/kg via iv, caused a significant decrease in LVSP, LVEDP and dp/dtmax, as well as in P-R interval and HR, but RVP increased and an ischemic degeneration found on S-T interval, which appeared particulally above 20mg/kg and at the sametime the vertricular premature beats seen too On ECG.
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