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《Journal of Anhui Traditional Chinese Medical College》 2001-01
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EFFECTS OF SHENXIANG YANGWEI POWDER ON PRECANCEROUS LESION IN CHRONIC ATROPHIC GASTRITIS

SUN Wei feng,SUN Gui hua,HUA Pei xian,LI Zi xu, CHENG Jie luang,TAO Wei ping,ZHONG Wu zhuang (General Hospital of Guangzhou Military Area,PLA,Guangdong Guangzhou 510010,China)  
Objective:To observe the therapeutic effect of shenxiang Yangwei powder(SXYWP) on atrophic gastritis and the reversal therapeutic effect on precancerous lesions.Method:The study included 68 patients diagnosed through gastroscopy and pathological examination.They were divided into treatment group and control group at random.55 patients in treatment group took SXYWP;17 patients in control group took Houtoujun tablets.Both groups took their drugs for 12 weeks.Expermental study:①To observe the effects of SXYWP on the blood flow in the gastric mucosa of rabbits;②To observe protective effects of SXYWP on the epithelial cells in gastric mucosa of rats by the injury of alcohol;③To observe effects of SXYWP on the experimental chronic atrophic gastritis model in Wistar rats.Result:Preventive and therapeutic effect in treatment group was better than that of control group.the total effective rate in treatment group was 92.16%,and 70.59% in control group.The difference between them was significant(P0.05).The experiments proved that SXYWP evidently promoted the blood flow in the gastric mucosa of rabbits,abated the injury of the gastric mucosa of the white rats by alcohol,and also had preventive effect on lesions and secretive function of experimental chronic atrophic gastritis model.Conclusion:SXYWP has good curative effect on atrophic gastritis and can reverse precancerous lesions.
【CateGory Index】: R259.7
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