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《Journal of Anhui Traditional Chinese Medical College》 2003-05
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Clinical Study on Treatment of Liver Fibrosis Due to Hepatitis B With Yigan Sanhao and Radiation of Near Infrared Message

TONG Guang dong, ZHOU Da qiao, QI Yan ping, LIU Ji qing, GAO Hui, HE Jin song, RAO Wei liang, XIE San ying, PENG Li sheng (Shenzhen Hospital Attached to Guangzhou University of Traditional Chinese Medicine, Guangdong Shenzhen 518033,China)  
To observe the efficacy of Yigan Sanhao (YGSH), a traditional Chinese prescription for hepatitis B, combined with radiation of near infrared message by instrument of liver disease (DSG ⅠILD) in treatment of liver fibrosis due to hepatitis B. Method: Two hundreds and thirty four inpatients of liver fibrosis due to hepatitis B were divided into YGSH treated group (n=76),radiation of near infrared message treated group (n=73) and combined treatment group (n=85).On the basis of general treatment including drugs such as Diammonii Glycyrrhizinatis Injection and Danshen Compound Injection, patients were treated with external application of YGSH, radiation of infrared message by DSG-ⅠILD and combined treatment of YGSH and DSG ⅠILD, respectively. The clinical symptoms, syndromes, liver function, PGA, 3 indexes of liver fibrosis (hyaluronic acid, laminin and collagen Ⅳ) and the blood stream capacity of liver were observed. The clinical symptoms and signs of three groups were all improved, and the combined treatment is superior to the other two treatments in improving the clinical symptoms. After treatment, the liver function of three groups all recovered, but there was no significant difference among three groups.The combined treatment was superior to the other two treatments in improving PGA, 3 indexes of liver fibrosis and blood stream capacity of liver. Conclusion: The combined treatment of YGSH and DSG ⅠILD could effectively treat liver fibrosis due to hepatitis B,and its effects are superior to those of YGSH or DSG ⅠILD alone.
【Fund】: 广东省深圳市科研资助项目 (2 0 0 2 0 4 2 32 )
【CateGory Index】: R259.7
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