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《Journal of Anhui Traditional Chinese Medical College》 2003-05
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Effects of Salvia Miltiorrhiza Injection and Astragalus Membranaceus Injection on Liver Function and Serum Marks of Hepatic Fibrosis in Liver Cirrhosis Patients

CHEN Jian, CHEN Zhe, HUANG Xue qiang, LU Ming, ZHANG Jue ying, YANG Long, CUI Jie (Shanghai Corps Hospital of Chinese People′s Armed Police Forces, Shanghai 201103, China)  
Objective:To study the effects of combined therapy of Salvia miltiorrhiza Injection(SMI) and Astragalus membranaceus Injection(AMI) on liver function and serum marks of hepatic fibrosis in liver cirrhosis patients. Method:One hundred and sixty nine patients with liver cirrhosis were divided into 4 groups at random, they received 28 day intravenous therapy with Diammonium Glycyrrhizinate Injection,SMI,AMI or combined with AMI,respectively. Their liver function and serum marks of hepatic fibrosis were examined before and after treatment. Result: Liver function of those patients in Salvia miltiorrhiza group, Astragalus membranaceus group and combined therapy group was significantly improved compared with that in control group(P0.05), and the plasma albumin in Astragalus membranaceus group and combined therapy group was markedly improved in comparison with that in Salvia miltiorrhiza group(P0.05). The amount of serum marks of hepatic fibrosis of those patients in Salvia miltiorrhiza group, Astragalus membranaceus group and combined therapy group decreased significantly compared with that in control group(P0.01), and in combined therapy group, the marks were lower than those in Salvia miltiorrhiza group, Astragalus membranaceus group(P0.05). Conclusion:Both SMI and AMI can improve liver function and reduce the amount of serum marks of hepatic fibrosis in liver cirrhosis patients, but combined therapy may get better curative effect.
【CateGory Index】: R575.2
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