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《Journal of Anhui Traditional Chinese Medical College》 2013-01
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Clinical Efficacy and Safety of Sanqi Tongshu Capsules in Treatment of Ischemic Stroke: A Systematic Review

XIA Wei1,YUAN Dong-chao1,KONG De-zhao1,ZHANG Zhe2,LUO Zhi-bo2,GUAN Xue-feng2,YANG Guan-lin2(1.Liaoning University of Traditional Chinese Medicine,Liaoning Shenyang 110032,China;2.Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Liaoning Shenyang 110032,China)  
Objective To evaluate the clinical efficacy and safety of Sanqi Tongshu Capsules,which are prepared from Panax notoginseng and used for promoting blood circulation and removing blood stasis,in the treatment of ischemic stroke by a systematic review.MethodsA literature search was performed using network databases including CNKI,CBM,CQVIP,and Wangfang Data according to certain inclusion and exclusion criteria;the literature included the papers on treatment of ischemic stroke with Sanqi Tongshu Capsules published up to July 2012.The methodological quality of the included studies was evaluated systematically,and relevant data were extracted.A meta-analysis was performed using Review Manager 5.1.ResultsA total of 9 studies were included in the analysis.There were no significant heterogeneity among the studies(χ2= 10.20,degree of freedom=8,P= 0.25,I2=22%).The experimental group(treated with Sanqi Tongshu capsules) showed a significantly better response than the control group(receiving conventional treatment)(OR=3.34,95%,CI=2.30-4.84).ConclusionSanqi Tongshu Capsules have better clinical efficacy than conventional treatment in ischemic stroke and show promise for clinical application.
【Fund】: 辽宁省科学技术计划项目(2010225034);; 辽宁省社会发展攻关计划项目(2010225034)
【CateGory Index】: R743.3
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