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Cox Regression Analysis of Relationship between Body Constitution and Recurrence in Patients with Primary Liver Carcinoma

GUO Yu-yu;CHEN Hong-yun;ZHAI Xiao-feng;LIU Qun;CHEN Zhe;Department of Oncology,Changhai Hospital Affiliated to The Second Military Medical University;  
Objective To explore the relationship between traditional Chinese medicine(TCM)body constitution and recurrence in patients with primary liver carcinoma(PLC),in order to provide a basis for the prediction and prevention of liver recurrence.Methods The clinical characteristics of 109 surgically treated patients with PLC,who were admitted to the Department of TCM and the Department of Interventional Therapy in our hospital from January to December,2009,were summarized.The types of their TCM body constitution were analyzed.The relevant factors influencing postoperative recurrence of PLC were subjected to univariate and multivariate Cox regression analysis.Results According to the results of Cox regression analysis up to April 1,2010,there were significant differences in age,clinical stage,classification of liver function,and history of drinking between patients with and without postoperative recurrence of PLC(P0.05).Age,clinical stage,history of hepatitis B,Yang deficiency constitution and blood stasis constitution entered into the Cox regression model.Conclusion Age,clinical stage,history of hepatitis B,and history of drinking are risk factors for postoperative recurrence of PLC.The higher scores of yang deficiency constitution and blood stasis constitution patients have,the sooner PLC recurs after surgery.
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