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《Journal of Anhui University of Chinese Medicine》 2017-04
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Clinical Effect of Tongdu Tiaoshen Acupuncture in Treatment of Acute Cerebral Infarction with Wind-phlegm Stasis Syndrome

ZHANG Ling;ZHANG Guo-qing;ZHU Ling-ling;HAN Wei;The Second Affiliated Hospital of Anhui University of Chinese Medicine;  
Objective To investigate the mechanism of action of Tongdu Tiaoshen Acupuncture in the treatment of acute cerebral infarction based on the levels of inflammatory factors.Methods A total of 40 patients with acute cerebral infarction with wind-phlegm stasis syndrome were randomly divided into treatment group and control group,with 20 patients in each group.The patients in the control group were given treatment to improve cerebral circulation,inhibit platelet aggregation,and protect the nerves,and those in the treatment group were given Tongdu Tiaoshen Acupuncture in addition to the treatment in the control group.The modified Rankin scale(mRS)and National Institutes of Health Stroke Scale(NIHSS)were used to evaluate neurological defects after cerebral infarction,and the plasma levels of interleukin-6(IL-6)and high-sensitivity C-reactive protein(hs-CRP)were measured before and after treatment.Results The treatment group had a significantly better clinical outcome than the control group(P0.05).After 1week of treatment,both groups had a significant reduction in IL-6level(P0.05)and a significant increase in hs-CRP level(P0.05),and the treatment group had significantly lower levels of IL-6and hs-CRP than the control group(P0.05).After 4weeks of treatment,both groups had significant reductions in the levels of IL-6and hs-CRP(P0.05),and there were no significant differences in the levels of IL-6and hs-CRP between the two groups(P0.05).After 4 weeks of treatment,both groups had significant reductions in NIHSS and mRS scores(P0.05),and the treatment group had significantly greater reductions compared with the control group(P0.05).Conclusion Tongdu Tiaoshen Acupuncture can improve neurological defects in patients with acute cerebral infarction with wind-phlegm stasis syndrome,possibly by reducing the plasma levels of IL-6and hs-CRP.
【Key Words】: Tongdu Tiaoshen Acupuncture Acute cerebral infarction Interleukin-6 High-sensitivity C-reactive protein
【CateGory Index】: R246.6
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