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《Chinese Journal of Cancer》 1991-01
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Huang Pei-sheng, WANG Yong (Department of Pathology, Fujian Medical College, Fuzhou, 350000)  
The binding of RcA to paraffin sections of sixty-six primary liver carcinoma and forty-one non-neoplastic liver tissue was examined by the ABC immunohistochemical method. The positive staining reaction of RcA receptor was recognized by the occurrenceof brown granular reaction product in the cytoplasm or on the cell menbrane. The positive rate in 66 cases of primary liver carcinoma was 86.4% (57/66). In 10 cases of normal liver tissue, in 9 cases of hepatitis and 22 cases of liver cirrhosis, RcA binding was all negative. These results suggest that RcA binding might be used as a new method for the diagnosis and differential diagnosis of primary liver carcinoma. The study showed that RcA receptor distribution is related to the differentiation of liver carcinoma. There was no relation between the RcA positive rate and the differentiation of liver carcinoma. The positive reaction was observed in the liver cells surrounding the cancer. A conclusion can be made that these RcA receptor positive liver cells might be a precanerous lesion of primary liver carcinoma.
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【Secondary References】
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