FLOW- CYTOPHOTOMETRIC ANALYSIS OF PROLIFERATIVE CHARACTERISTICS OF PAROTID CARCINOMA CELLS
YANG Bing ZHANG Yong-fu (Department of stomatology, Jiangxi Medical College Nanchang 330000)
Using flow-cytometry, the DNA content of the cells in 5 samples of normal salivary tissues, 36 cases of benign salivary tumors and 50 cases of parotid carcinoma was analysed. The results showed that the differences of DI and PI among different ages, sexes, tumor sizes, and TNM stages were not significant (P0.05). The DI and PI of poorly differentiated parotid carcinomas were much higher than those of well differentiated parotid carcinomas (P0.05). The DI and PI were closely related to the lymph node metastasis (P0.001). The DI and PI of carcinomas with paralysis of facial nerves and with disease-free period less than 5 years were remarkably higher than those of carcinomas with non-kivo-Ived facial nerves and with disease-free period more than 5 years (P0.01). The abovementioned results indicated that the DI and PI can reveal the cell proliferative kinetic characteristics and they also provide reliable and objective parameters for assessing degree of differentiation grade of malignancy, bilolgical behavior and prognosis of parotid carcinomas.