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《Chinese Journal of Cancer》 1991-01
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CLINICAL STUDY ON 800 CASES OF PROGRESSING AND ADVANCED PRIMARY BRONCHOGENIC CARCINOMA

JIANG Bai-kun (Yunnan Tin Corporation Hospital, Gejiu, Yunnan 661400)XUAN Xiang-zhen (Labor protection Institute, Yunnan Tin Corporation .Yunnan 661400)  
From 1975 to 1985, 1158 cases of primary lung cancer were treated inour hospital. Among them, 800 progressing and advanced cases were studied for the pathologic classification and the characteristics of metastasis.In this group, the incidence of squamous cell cancer was highest (58.5% ,468/800). Met-astases of squamous cell cancer to lymph nodes, bone, brain, etc. were most common. Pl-eural effusion complicated with atelectasis, superior vena cava syndrome and hoarseness (par- alsis of vocal cord due to involvement of recurrent laryngeal nerve) were also common in squamous cell cancer. The incidence rate for small cell anaplastic carcinoma was 16.9% (138/ 800), most metastases were observed in the liver and lymph nodes, the incidence rate for adenocarcinoma was 13% (104/800), the main metastases presented in pleural effusion. In this series most patients had metastases to important organs, the median survival time was 6-8 months in average. When clinical symptoms is due to the metastasis to a certain organs, proper chemotherapy of radiotherapy might relieve the symptoms and prolong the survival time. When the following symptoms and signs with unknown causes such as enlargemeut of supraclavicular lymph nodes, local ostealgia, horseness, and apyreitc pleural effusion etc were detected in middle-aged and aged patients the doctors should maintain vigilance for the possibility of lung cancer metastasis, further examinations would be necessary. New approuches to the prevention and therapy of metastsis of lung cancer await burther investigation and exploration.
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