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《Oncology Progress》 2018-02
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Clinical efficacy of wedge resection and anatomical lobectomy in the treatment of early non-small cell lung cancer

ZHANG Ning;ZHU Xiaoming;XU Lei;LI Jiwei;WU Sen;CHEN Zhong;WEI Li;Thoracic Oncology Center, He'nan Provincial People's Hospital;  
Objective To observe the effect of wedge resection and anatomical lobectomy in the treatment of early non-small cell lung cancer(NSCLC). Method 92 cases of early NSCLC patients were retrospectively analyzed, these patients were stratified as study group that received thoracoscopic wedge resection(n=46), or control group that was administered with anatomical lobectomy. The intraoperative blood loss, operative time, postoperative hospital stay, postoperative local recurrence, survival rate, recurrence and complication of the two groups were statistically analyzed, and the clinical effect of thoracoscopic sublobectomy was evaluated. Result The intraoperative blood loss, operative time and postoperative hospital stay in the study group were significantly lower than those in the control group(P0.01). The local recurrence rate and the incidence of complications in study group were lower than those in the control group, but the differences were not statistically significant(P0.05). Patients were followed for 9 to 36 months, and 5 deaths were observed in study group, with the cumulative survival rate being 89.1%; there were 9 deaths in control group, and the cumulative survival rate was 80.4%, the 3-year cumulative survival rates demonstrated no significant difference between the two groups(χ~2=1.322, P0.05). Conclusion Thorascopic wedge resection, which can shorten the operative time and hospital stay, reduce intraoperative blood loss with minimal surgical wound, and would neither increase the local recurrence rate nor reduce the long-term survival rate, is a safe and effective treatment.
【CateGory Index】: R734.2
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