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《Oncology Progress》 2018-02
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Retrospective analysis of bone metastases in 55 patients with lung cancer

MA Yujie;LI Junling;CHENG Fang;WANG Jing;CHEN Dongna;LIU Na;HAO Xuezhi;Department of Medical Oncology, Beijing Chaoyang District Sanhuan Cancer Hospital;Department of Medical Oncology, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College;  
Objective To investigate the clinical features, diagnosis and treatment of bone metastases in advanced lung cancer with bone metastases. Method The clinical data of 55 cases of lung cancer with bone metastases were retrospectively analyzed. Result Of the 55 cases of lung cancer with bone metastases, 70.91% were adenocarcinoma, the main metastatic sites were vertebral body, ribs, pelvis, scapula, femur and skull. Multiple lesions accounted for 76.36%(42/55), and isolated lesions accounted for 23.64%(13/55). Diagnostic methods included single-photon emission computed tomography(ECT), magnetic resonance(MRI) and CT examination. Zoledronic acid combined with analgesics was the main treatment, and there were 19 patients suffered from bone pain, while symptoms were relieved after treatment in15 patients. Conclusion Lung adenocarcinoma is most common in bone metastases of advanced lung cancer, and the metastatic site is mainly vertebral body. Zoledronic acid combined with analgesics can relieve bone pain, improving the quality of life for patients. Routine scan should be integrated in the clinical care for advanced lung cancer patients.
【CateGory Index】: R734.2
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