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《Oncology Progress》 2018-02
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Study on the related factors of bladder cancer that invades prostate

LIU Taiyang;LI Jie;GUI Qi;WEN Xiuhua;ZHANG Hui;FENG Zhigang;Department of Urinary Surgery, Zhumadian Central Hospital;  
Objective To explore the factors related to the invasion in prostate in patients with bladder cancer, and to lay the clinical basis for the preservation of prostate. Method 135 patients were enrolled in this retrospective study, and the factors associated with prostate invasion in bladder cancer were analyzed by Logistic stepwise regression. Result Among the 135 patients, there were 14(10.4%) patients with prostate invasion. In multivariate analysis, tumor site, tumor diameter, distance of tumor from bladder neck, and tumor grading were independent risk factors of prostate invasion in bladder cancer. Compared with tumors not in trigone or neck, those in trigone or neck of bladder were associated with1.784 times of increased risk of prostate invasion; every 1 cm increase of tumor diameter indicated 2.375 times of higher risk of prostate invasion; while as the distance of tumor from the bladder neck decreased every 1 cm, the risk of prostate invasion would increase 2.079 times; the risk of invasion in patients with higher grade of bladder cancer was 1.684 times that of patients with lower grade of disease. Conclusion Tumor located in the bladder trigone or neck, tumor close to bladder neck, higher grade of disease, and tumor with greater diameter are the main risk factors of prostate invasion,which should be addressed in monitoring, and in selecting the scope of surgery.
【CateGory Index】: R737.14
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