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《Oncology Progress》 2018-02
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Analysis of pulmonary infection status and related factors after liver resection in patients with hepatocellular carcinoma

REN Rui;WANG Wei;LU Changyou;Department of General Surgery, the First People's Hospital of Yibin;  
Objective To explore the factors influencing the postoperative pulmonary infection in patients with hepatocellular carcinoma, and to provide the scientific basis for future clinical intervention and treatment. Method 210 patients were included in the analysis, of which the general demographic characteristics, including age, gender and BMI were collected. The operative time, intraoperative blood transfusion and intraoperative blood loss and other data, as well as the time to discharge after surgery, postoperative albumin, hemoglobin and white blood cells(WBC) and other postoperative profiles were gathered, Logistic stepwise regression analysis was used to analyze the related factors. Result 57 cases had pulmonary infection after hepatectomy accounting for 27.14%(57/210) of all patients. Multivariate analysis found that the risk of pulmonary infection in patients with a history of smoking was 1.809 times that of patients without smoking history; and patients with pleural effusion had 2.330 times higher risk of pulmonary infection than that in patients without pleural effusion; the risk of developing pulmonary infection increased 2.029 times with every 1-year increase in age; and that increased 1.759 times for every additional day before discharge; patients gained 2.669 times higher risk of pulmonary infection for every additional day of peritoneal drainage. Conclusion The incidence of pulmonary infection after hepatectomy in hepatocellular carcinoma is high, history of smoking, postoperative pleural effusion, elderly patients, longer time to discharge and time needed for peritoneal drainage are independent risk factors for infection.
【CateGory Index】: R563.1;R735.7
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