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《Journal of Bengbu Medicine College》 2003-01
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Bisoprolol in treatment of congestive heart failure of caronary heart disease

FENG Yan xian,YU Qiang (Department of Cardiovascular Diseases,Bengbu Third People's Hospital,Anhui 233000 ,China)  
Objective:To observe the effect of bisoprolol(β receptor paralyzer) in the treatment of congestive heart failure of caronary heart disease.Methods:Thirty seven patients who were graded as Ⅲ to Ⅳ caronary heart disease according the criteria by NYHA were treated with digitalis,diuretic and angiotensin converting enzyme inhibitor.After getting into a relatively stable condition,they were divided into two groups:treatment group(17 cases) and control group(20 cases,routine treatment).The treatment group received,besides routine treatment,bisoprolol(1.25 mg/d) which was increased 1.25 mg every two weeks.The max dosage was 5 mg/d.The treatment course lasted for 12 weeks.Results:The LVEDD and LVESD of the two groups before treatment significantly were reduced( P 0.01),EF was increased obviously( P 0.01),and heart rate was reduced greatly( P 0.01);After treatment,the LVEDD\,LVESD,EF,heart rate and ventricular number in the group with bisoprolol more improved significantly( P 0.01, P 0.01, P 0.01, P 0.01, P 0.05,respectively).Conclusions:Bisoprolol(β receptor paralyzer) can reduce the ventricular volume which had been recombinatively repaired and the incidence rate of ventricular arrhythmias.It can also improve EF and slow down heart rate.
【CateGory Index】: R541.6
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【Co-citations】
Chinese Journal Full-text Database 3 Hits
1 ZHANG Jin-min (Shanghai University Hospital, Shanghai, 200083, China);Curative Effect of Small Dose Dopamine for Chronic Heart Failure Treatment in Aged Patients[J];Anhui Journal of Preventive Medicine;2004-03
2 HU Ling,LI Meng,CHENG Wei-hua,WANG Ke-ming,WANG Yue-lan (Department of Acupuncture and Moxibustion,Anhui College of TCM,Anhui Hefei 230038,China);EFFECT OF ACUPUNCTURE COMBINED WITH DUSHENG INJECTION ON MECHANICAL PARAMETERS OF CARDIAC MUSCLE IN RABBITS WITH ACUTE HEART FAILURE[J];Journal of Anhui Traditional Chinese Medical College;2000-06
3 ZHENG Xiao-rong,WANG Yi-hu,ZHANG Can-jiu (Department of Polyclinic,Xijing Hospital,Fourth Military Medical University,Xi'an,Shanxi 710032,China);Clinical observation on treatment of heart failure patients with China-made bisoprolol fumarate[J];Editorial Departmert of Chinese Journal of Geriatric Cardiovascular and Cerebrovascular Disease;2002-02
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