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《Journal of Bengbu Medicine College》 2003-01
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Comparatine analysis of HBV DNA and HBV-M in the serum of patients with hepatitis B

CUI Zhuo,WANG Shu min (Department of Infectious Diseases,Affiliated Hospital of Bengbu Medical College,Anhui 233004,China)  
Objective:To explore the positive rate of HBV DNA in the serum of patients with hepatitis B in different markers and its clinical significance.Methods:Serum HBV DNA was tested by polymerase chain reaction(PCR),hepatits B virus markers(HBsAg?HBsAb?HBeAg?HBeAb?HBcAb) were detected using enzyme linked immunosorbent assay(ELISA).Results:In 212 HBsAg+/HBeAg+/HBcAb+ samples,all the PCR results were positive,the positive rate was 100%;In 158 HBsAg+/HBeAb+/HBcAb+ samples,HBV DNA positive rate was 39.2%(62/158);In 55 HBsAg+/HBcAb+ samples,HBV DNA positive rate was 54.5 %(30/55);In 40 HBsAb+/HBeAb+/HBcAb+ samples,HBV DNA positive rate was 12.5%(5/40).Conclusions:The results reveal that the PCR assay is more sensitive.Only by testing HBV DNA,can we monitor the true state of HBV infection and amplification.
【CateGory Index】: R512.62
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