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《Journal of Bengbu Medical College》 2006-05
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Docetaxel combined with cisplatin for treatment of advanced breast cancer

SUN Hui-juan,QIN Feng-zhan,ZHENG Rong-sheng,WANG Zi-shu,WANG Hong-ya,LIU Tie-cheng(Department of Medical Oncology,Affiliated Hospital of Bengbu Medical College,Bengbu 233004,China))  
Objective:To observe the clinical response and side effect of docetaxel combined with cisplatin in treatment of advanced breast cancer.Methods:All the patients were administered docetaxel 70 mg/m~2 iv drip d1,and dexamethasone 7.5 mg bid d1-3 twenty-four hours before chemotherapy.Cisplatin 25-30 mg/m~2 was given iv drip d1-3,every 3 weeks as a circle.Results:Five cases presented complete remission(CR),and 29 cases partial remission(PR).The total response rate(PR+CR) was 72.3%.The main toxicity was neutropenia,nausea and vomiting.Conclusions:The regimen of docetaxel combined with cisplatin has significant antitumor activity for patients with advanced breast cancer.
【CateGory Index】: R737.9
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