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《Acta Zoologica Sinica》 2003-01
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Morphological change in rat jejunal mucosal epithelia and cell proliferation and apoptosis in different months

WANG Li LI Jian CHEN Yan-Min DUAN Xiang-Lin ** (College of Life Science,Hebei Normal University,Shijiazhuang 050016,China)  
Cell proliferation and apoptosis of the jejunal mucosal and glandulose epithelium from natality to the postnatal 12th month were observed using immunocytochemistry(ICC),the TUNEL method and analysis of morphometry.The height of the jejunal villus, thickness of the jejunal muscle and the number of gobelet cells in the jejunal mucosal and glandulose epithelium were measured using BeiHang analytical software and analysed by STAT.The results show that:1)PCNA positive cells of the jejunal glandulose recess were found at natality and increased in number from then to the postnatal 3rd month.The number of PCNA positive cells peaked in the postnatal 3rd month and decreased from then on; 2)the number of apoptotic cells also peaked in the postnatal 3rd month,showing a similar trend to that of the PCNA positive cells; 3)The height of the jejunal villus increased from natality,peaked in the postnatal 3rd month and decreased from then on.The thickness of the jejunal muscle appeared to peak in the postnatal 3rd week, and 12th month.The number of goblet cells of the jejunal mucosal increased rapidly in the postnatal 3rd week and had a linear correlation with age [Acta Zoologica Sinica 49(1):91-97, 2003].
【Fund】: 河北省自然科学基金资助项目 (No 39715 8)~~
【CateGory Index】: Q954.4
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