Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Beijing Polytechnic University》 2004-01
Add to Favorite Get Latest Update

Force Signal Transfer Pathway and Mechanism in Cell

ZENG Yan-jun, QIAO Yuan-hua, ZHANG En-ping, XU Xiao-hu, ZHAO Hu, YU Xiao-jun, XU Hong, HU Jin-lin (College of Life Science and Biomedical Engineering, Beijing University of Technology, Beijing 100022, China; Medical College of Shantou University, Shantou, Guangdong 515031, China; Beijing Microview New Era Science & Technology Co. Ltd, Beijing 100080, China )  
In order to further make clear cell mechanics, the authors introduce the transfer pathways of force signal such as mechanotransduction, mechanoreceptors, mechanosensitive ion channels and so on. There exist mechanosensitive ion channels in both endothelial and nonendothelial cells and these channels to regulate ion transfer may play important role in cell sensing mechanical force and transforming it into biochemical signal. On this basis, the authors propose that its transfer mechanism might have ligand and receptor, structural change and the mechanism of platelet in the blood congulation, etc. The combination between the molecules of receptor and ligand is idiosyncratic and reversible. The kinetic povrameters can be obtained according to the dependence of adhesion probability on their contact time.
【Fund】: 国家自然科学基金资助项目(39600040;10172096);; 北京市自然科学基金资助项目(3982005).
【CateGory Index】: R318.01
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 Li Run-guang, Shao Jing-fan, Wei Ming-fa,et al 1Department of Pediatric Surgery, 2Department of Hematology, 3Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China;Influences of stretch stress on cell proliferation and cell cycle of human bone marrow mesenchymal stem cells[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2007-07
【Citations】
Chinese Journal Full-text Database 1 Hits
1 Li Xiufeng Zeng Yanjun ( Biomechanics Laboratary, Beijing Polytechnic Universityl Beijing 100022, China) Zhao Hong Zhuang Fengyuan (Rheology Department, Research Institute of China-Japan Friendship Hospital, Beijing 100029, China);ADVANCE IN THE RESEARCH OF RECEPTOR- LIGAND BINDING KINETICS[J];Advances In Mechanics;2000-04
China Proceedings of conference Full-text Database 1 Hits
1 Woodruff School of Mechanical Engineering and Coulter Department of Biomedical Engineering Georgia Institute of Technology, Atlanta, GA 30332, USA;Kinetics and Mechanics of Cell Adhesion[A];[C];2001
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 WU Minghai, SUN Xiaoming, GUAN Jinghua,QIN Yanjiang. Department of Physics,Shangdong University, Jinan 250012;Experimental Studies on Mechanisms of Extracorporeal Thrombus Formation[J];Beijing Biomedical Engineering;2003-02
2 Ding Kuke~(1),XU Lili~1,WANG Chunyan~1,HUANG Juying~1,HU Jinlin~3,SONG Xiaoyan~2,ZENG Yanjun~2 1 Institute of Biomedical Engineering in Capital University of Medical Sciences,Beijing 100069;2.Biomedical Engineering Center in Beijing University of Technology,Beijing 100022;3.General Hospital of PLA,Beijing 100853;The Effects of the Fluid Forces on the Expression of the Proto-Oncogenes c-fos and c-myc[J];Beijing Biomedical Engineering;2006-02
3 GAO Huijuan~1),HUANG Yongqin~1),LI Xinyi~2).1) Department of Neurology,Jishan People's Hospital,Jishan 043200,Shanxi;2) Department of Neurology,the First Hospital of Shanxi Medical University,Taiyuan 030001,Shanxi;The risk factors of hemorrheology in patients with acute intracerebral hemorrhage[J];Clinical Medicine;2006-01
4 ZHENG Xiao-lin1,2,CHANG Jing1,LIAO Yan-jian1,YANG Jun1,LIU Chang1(1.College of Bioengineering,Chongqing University,Chongqing 400030,China;2.National Key Laboratory Fundamental Science of Micro/Nano-device andSystem Technology,Chongqing 400044,China);Study on practicality of micro-channel measurement system for red blood cell deformability[J];Transducer and Microsystem Technologies;2009-07
5 WANG Chang-De,XIA Ya-Yi,ZHANG Cheng-Jun Institute of Orthopedics,Second Hospital,Lanzhou University,Lanzhou 730000,China;Effects of fluid shear stress and cytoskeletal disruption on the actin cytoskeleton[J];Journal of the Fourth Military Medical University;2009-19
6 SU Jing (The Harbin Medical University,Harbin 150080,China);Study about the Relationship Between Plasma Fibrinogen Level and Pathological Changes of Lower Limbs' Arteries in Patients with Diabetes Mellitus[J];Heilongjiang Medical Journal;2008-06
7 TANG Ying1,WU Jian-jun,HUANG Guang-hua,et al.1Department of Experimental Medicine,Wuhan General Hospital,Guangzhou Military Command,Wuhan Hubei 430070,China;Effects of LSPC on Hemorheology in Hyperlipidemia Model Rats[J];Military Medical Journal of South China;2008-04
8 YANG Fen, LI Ying hui.Institute of Space Medico Engineering,Beijing 10094,China;Roles of Integrins and Cytoskeleton in Cellular Mechanotransduction.[J];Space Medicine & Medical Engineering;2002-04
9 TUERDI Abulikemu~1 AIZEZI Renaguli~2 JIN Wei~2 UPUR Halmurat~2 ABUDOUREYIMU Shajidan~(1,3) 1.First Affiliated Hospital,Xinjiang Medical University,Urumqi 830054,China 2.Faculty of Traditional Uighur Medicine,Xinjiang Medical University,Urumqi 830054,China 3.College of Basic Medicine,Xinjiang Medical University,Urumqi 830054,China;Study on the Prethrombotic State in Diabetes Mellitus[J];Science & Technology Review;2008-11
10 JIA Wei-hua,TIAN Gui-ling,ZHOU Li-chun,ZHANG Tian-lin Department of Neurology,Beijing Chaoyang Hospital(west campus),Capital University of Medical Sciences,Beijing 100043,China;Relationship about wall oscillatory shear stress and plaque in carotid artery in ischemic stroke[J];Clinical Focus;2006-20
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 CHEN Xiao li, SONG Kai yuan et al Acupuncture, Moxibustion and Tuina College, Chengdu University of Traditional Chinese Medicine (Chengdu,610075,China);Analgesic Effect and Influence of Plasma 5-HT Content by Electric Needle Acupuncturing the He-gu(LI4) Point on Soft Tissue Injury Rabbits in Different Hour[J];Journal of Chengdu Unversity of Tarditional Chinese Medicine;2001-03
2 LiJian; Chen Wugao(Department of Physics, Central China Normal University, Wuhan,430070);Research on the Mechanism of Laser Acupuncture and Moxibustion[J];Journal of Optoelectronics.laser;1994-05
3 Li Zhongming;Chen Wugao(Department of Physics,Central China Normal university,Wuhan,430070);Pressure Effects of Acupuncture and Moxibustion of Laser[J];Journal of Optoelectronics.laser;1996-03
4 Xiang Yang Ding Zhibao(Biology Department of Changsha Electric Power University,Changsha 410077);The Inquiry in Effect Mechanism of Laser Biology[J];Journal of Optoelectronics.laser;1997-06
5 Weidong BIAN,Suqin SUN,R.NS.WONG1,Qun ZHOU and Xingyao HU Department of Chemistry,Tsinghua University,100084 Beijing 1Department of Biology,Hong Kong Baptist University;Study on Thermal Unfolding Process of Trichosanthin by FTIR Spectroscopy[J];SPECTROSCOPY AND SPECTRAL ANALYSIS;2000-04
6 HAN Rong-bin, SHI Zhong-dong, YANG Wen-li, YUAN Ying-jin (Department of Pharmaceutical Engineering, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, China);Effect of Shear Stress on Suspension Cultures of Taxus chinensis var. mairei[J];The Chinese Journal of Process Engineering;2003-02
7 Tan Wen song;Dai Gance;Chen Zhihong and Chen Yinliang(Research Institute of Biochemical Engineering ECU ST,Shang hai 200237);Physical Damage of Hybridoma Cells in Bioreactors[J];JOURNAL OF EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY;1996-03
8 Shen Zhengwu Wu Lianfen (Shanghai Institute of Organic Chemistry, Shanghai 200032, China);Advances in Taxol Research[J];PROGRESS IN CHEMISTRY;1997-01
9 QI Meng-chun, HU Jing, ZOU Shu-juan, HAN Li-chi, LUO En. (Key Lab. of Oral Biomedical Engineering of Ministry of Education, Sichuan University, Chengdu 610041, China);The Changes of Cytoskeleton F-actin in Rat Bone Marrow Mesenchymal Stem Cells and Calvarial Osteoblasts under Mechanical Strain[J];West China Journal of Stomatology;2005-02
10 LI Yan~1, JIAO Jian-ling~2, LIU Cheng-yi~ 1, 3 , LIU Song-hao~4 (1. Laser Sport Medicine Laboratory, South China No rmal University, Guangzhou 510631,Guangdong, China; 2. Department of Traditional Chinese Medicine, Jinan University, Guangzhou 5106 32, Guangdong, China; 3. The Key Laboratory of Biomedical Photonics of Ministry of Education of China and State Key Laboratory of Laser Technology, Huazhong University of Science and Technology, Wuhan 430074 , Hubei, China; 4. School of Information and Optoelectronic Science and Engineering, South Ch ina Normal University, Guangzhou 510631, Guangdong, China) [WT5HZ];Recent Advance of Effects of Low Intensity Laser Irra diation on Cells[J];Acta Laser Biology Sinica;2003-01
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 YU Jing,XIE Ya-jia,XU Duo,ZHAO Shou-liang.(Department of Conservative Dentistry,School of Stomatology,Tongji University.Shanghai 200072,China);Effect of cyclic strain on cell morphology,viability and proliferation of human dental pulp cells in vitro[J];Shanghai Journal of Stomatology;2009-06
2 Huang Yan Fan Yubo(School of Biological Science and Medical Engineering,Beihang University,Beijing 100191,China);Research Advances in Effects of Mechanical Stimulation on Bone Marrow Mesenchymal Stem Cells[J];Journal of Biomedical Engineering;2010-04
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved