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《LABELED IMMUNOASSAYS AND CLINICAL MEDICINE》 2000-01
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Meta-analysis of the Significance of Plasma Endotheline in Coronary Atherosclerotic Heart Disease

Yu Xindong, Ma Zhongfu, Liu Xiuqin et al. (Internal Medicine Department, People′s Hospital of Gaoming City, Gaoming 528500))  
To investigate the significance of plasma endotheline (ET) levels in patients with different coronary heart diseases (CHD), synthetic quantitative analysis was used to study internal literatures on plasma ET change by means of Meta-analysis. The results showed that the levels of plasma ET in the patients with acute myocardial infarction (AMI), or unstable angina(UA), or stable angina(SA), were 2.34~0.92,3.66~0.76 or 5.50~0.84 times of standard deviation higher than those in the healthy control group, respectively. Moreover, plasma ET levels in patients with UA or AMI were 1.55~0.45 times or 2.98~0.28 times of standard deviation higher than those in patients with SA,respectively.And the levels of plasma ET in patients with AMI were 1.48~0.02 times of standard deviation higher than those in the patints with UA.Conclusion: The higher the plasma ET levels the patients had, the more serious CHD were. Plasma ET levels may be a new parameter as to monitor the sever degree of CHD.
【CateGory Index】: R541.4
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