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《Labeled Immunoassays and Clinical Medicine》 2017-11
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Effects of Microbial Enteral Nutrition on Serum Amylase,hs-CRP and Gastrointestinal Function in Children with Acute Pancreatitis at Different Stages

ZHU Li-jun;ZHU Li-hong;ZHU Li-xia;Tangshan City Fengrun District Chinese Medicine Hospital;  
Objective To investigate the effects of microbial enteral nutrition on serum amylase,hs-CRP and gastrointestinal function in children with acute pancreatitis at different stages. Methods A total of 120 children with acute pancreatitis who received treatment in our hospital from May 2012 to June 2016 were selected as the subjects of the study. All the children were randomly divided into the super-early group and the early group. The super-early group was treated with microbial enteral nutrition support after 24 hours of admission.In the early group,the microbial enteral nutrition support intervention was performed at 72 hours after admission. After treatment,the serum amylase,hs-CRP and gastrointestinal function were compared and analyzed. Results The rate of good nutrition tolerance in the early group was significantly lower than that in the super-early group( P 0. 05). There was no significant difference between the two groups in the mortality group. The length of hospital stay was 36. 94 ± 7. 19 d,which was significantly higher than that of the superearly group( 28. 79 ± 5. 89 d)( P 0. 05). The incidence of complications in the early group was significantly higher than that in the early group( P 0. 05). The incidence of hs-CRP in the super-early group was 89. 5 ±38. 2 mg/L,and it was significantly lower than that in the early group( 110. 5 ± 20. 2 mg/L)( P 0. 05).There was no significant difference in AMY level between the two groups before and after treatment( all P 0. 05). After treatment,the scores of gastrointestinal function of the two groups were significantly lower than those before treatment,and the difference of the data before and after treatment was statistically significant( P 0. 05). There was no significant difference between the two groups( P 0. 05). The scores of the patients in the super-early group( 0. 26 ± 0. 03) were significantly lower than those in the early group( 0. 69 ±0. 20)( P 0. 05). The difference between the two groups was statistically significant( P 0. 05). Conclusion The implementation of ultra-early micro-enteral nutrition in patients with acute pancreatitis can effectively improve the patient 's intestinal tolerance,meet the metabolic and nutritional needs of patients,shorten the hospital stay,and is conducive to early rehabilitation of patients.
【CateGory Index】: R725.7
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