Clinical Efficacy of Rosuvastatin Combined with Olmesartan in Elderly Hypertensive Patients with Hypercholesterolemia
ZHENG Su-mei;LI Hui;Tangshan City Fengrun District Chinese Medicine Hospital;
Objective To explore the efficacy of rosuvastatin combined with the clinical curative effect of losartan on Austria beauty of elderly hypertensive patients with hypercholesterolemia. Methods 87 cases of hypertension and hypercholesterolemia patients as test subjects in this study from June 2015 to June 2016 in our hospital,according to chronological admission patients were divided into observation group with 43 cases and 44 cases for the control group. The control group were treated with Fluvastatin and olmesartan,while the observation group were treated with statin rosuvastatin combined with olmesartan. The clinical efficacies were observed and the quality was measured and recorded before and after TC,TG,HDL-C,LDL-C,hs-CRP changes. The results were then analyzed and compared. Results After 3 months and 6 months treatments,the observation group performed better than the control group: the systolic blood pressure and diastolic blood pressure were lower than those in the control group( P 0. 05). After 3 months and 6 months treatments,the TC,TG,HDL-C,LDL-C and hs-CRP content of two groups were better than pre-treatment group( P 0. 05). There was no significant difference in left ventricular function( LVEF( %),LVPFR) between the two groups before and after treatment( P 0. 05). Two groups of patients had no obvious adverse reactions,whiel the observation group of patients with fatigue in 1 cases and the control group of patients with abdominal distension in 1 cases. In both cases,the patients were able to tolerate and there was no significant difference between the two groups( P 0. 05). Conclusion Rosuvastatin combined with olmesartan treatment of elderly hypertensive patients with hypercholesterolemia had good clinical efficacy. It significantly improves the patient's blood lipid index with a good safety and worthy of clinical application.
【CateGory Index】： R544.1;R589.2