Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Baoji University of Arts and Sciences(Natural Science Edition)》 2018-04
Add to Favorite Get Latest Update

Microcalorimetric study on the interaction of fraxinellone and magnetic nanocarriers

JIN Zhe-jun-yu;ZHAO Wei-wei;PU Xiao-hua;College of Chemistry and Chemical Engineering,Baoji University of Arts and Sciences;  
Purposes—To prepare Fe_3O_4@ZnAl_2O_4:Eu~(3+)@mSiO_2-APTES nanocarriers and determine the heat change of the nanocarriers on the loading and release procsses of fraxinellone.Methods—Fe_3O_4@ZnAl_2O_4:Eu~(3+)@mSiO_2-APTES nanocarriers were prepared with direct precipitation method.The obtained products were characterized with X-ray powder diffraction(XRD)and scanning electron microscopy(SEM),then the change in heat of loading and release procsses between the fraxinellone and the nanocarrier of Fe_3O_4@ZnAl_2O_4:Eu~(3+)@mSiO_2-APTES was observed with a microcalorimeter.Result—The core-shell nanocarrier with Fe_3O_4 as the core was prepared.Results shown that the binding effect on the drug was mainly hydrogen bond.Conclusion—The nanocarrier has a good prospect in drug loading and releasing.
【Fund】: 陕西省高校科协青年人才托举计划项目(20170707);; 陕西省植物化学重点实验室项目(17JS009);; 陕西省科技计划项目(2018JQ2056);; 宝鸡文理学院博士科研启动项目(ZK2017026)
【CateGory Index】: TB383.1;TQ460.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 3 Hits
1 HAO Xiao-Hong;ZHANG Cui-Miao;LIU Xiao-Long;LIANG Xing-Jie;JIA Guang;ZHANG Jin-Chao;College of Chemistry & Environmental Science,Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education,Chemical Biology Key Laboratory of Hebei Province,Hebei University;CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety,National Center for Nanoscience and Technology;;Recent Advances of Mesoporous Silica Based Multifunctional Nano Drug Delivery Systems[J];生物化学与生物物理进展;2013-10
2 KE Xue Department of Pharmaceutics,China Pharmaceutical University,Nanjing 210009,China;Advances in targeted drug delivery system[J];中国药科大学学报;2012-01
3 ZHOU Peng-ju, DENG Sheng-qi, GONG Qian-fei (Sichuan Industrial Institute of Antibiotics, China National Pharmceutical Group, Chengdu 610052, China);Recent development of targeted drug delivery system[J];药学学报;2010-03
Chinese Journal Full-text Database 10 Hits
1 CHU Minghua;CHEN Fang;LI Xiaoqi;LI Xuehui;College of Physical Science and Technology,Dalian University;;Preparation of Fe_3O_4/carboxyl chitosan magnetic composite particle loading drug[J];功能材料;2015-19
2 Chen Jiongliang;Liu Li;Xu Desheng;Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine;;Determination of rosmarinic acid in common selfheal fruit-spike effective components of colon target tablets[J];国际中医中药杂志;2015-07
3 Liu Dan;Zhang Liping;Liu Jun;Fu Shuang;Wu Shan;Academy of Medical and Pharmaceutical Science Qiqihar Medical University;;Removal of CTAB from Mesoporous Nano Silica by the Combination of Extraction and High Pressure Steam[J];广东化工;2015-12
4 HUANG Hai-yan;School of Applied and Chemical Engineering of Xichang College;;Research Progress of Magnetic Targeting in Physical Chemistry Targeting Preparation[J];广州化工;2015-01
5 ZHAN Lu-lu;YIN Dong-dong;WANG Xing-lin;WANG Zhuan;Pharmaceutical College of Henan University;Tianjin Institute of Pharmaceutical Research,State Key Laboratory of Drug Delivery Technology and Pharmacokinetics;;Progress in preparation techniques of colon-specific drug delivery system[J];中国新药杂志;2014-16
6 LI Yan-jie;WANG Ying;YIN Zhuo-lin;MA Feng;School of Chemistry and Pharmaceutical Engineering,Shandong Polytechnic University;Stair Chemical and Technology Co.,Ltd.;;Progress in Preparation and Application of Starch Microspheres as Drug Carriers[J];食品研究与开发;2014-12
7 WU Huiling;ZHANG Shuping;School of Science,University of Shanghai for Science and Technology;;Progress in the application of sodium alginate/nanomaterial composites[J];化工进展;2014-04
8 Chen Qinhua;Xiong Lin;Yu Fei;Affiliated Dongfeng Hospital,Hubei University of Medicine·Institute of Pharmaceutical Analysis and Drug Screening;;Research Advances on Bone Targeted Drugs[J];中国药业;2014-02
9 LUO Bing-hua①,DING Jie-qiong①,YAN Zhi-fei②,DING Hong② ①School of Pharmaceutics,Hubei University of Science and Engineering,Xianning 437100,China; ②School of Pharmacy,Shanxi Medical University,Taiyuan 030001,China;Release Characteristics of Adriamycin-PLGA Microspheres in vitro[J];解放军药学学报;2013-04
10 LIU Yun1,CHEN Fen1,YIN Fei2,DONG Jiang-nan2,YANG Xing-gang1,PAN Wei-san1(1.School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China;2.Department of Pharmacy,Liaoning Tumor Hospital,Shenyang 110042,China);Preparation and characterization of meloxicam-loaded nanostructured lipid carriers[J];沈阳药科大学学报;2013-02
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 Wang Wenqian1 Chen Linfeng2 Wen Yongqiang1** Zhang Xueji1 Song Yanlin2 Jiang Lei2(1.Research Center for Bioengineering & Sensing Technology,School of Chemistry and Biological Engineering,University of Science and Technology Beijing,Beijing 100083,China; 2.Institute of Chemistry,Chinese Academy of Sciences,Beijing 100190,China);Mesoporous Silica Nanoparticle-Based Controlled-Release System[J];化学进展;2013-05
2 Dong-Sheng Sun, Department of Hepatobiliary Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin 150086, Heilongjiang Province, China Jiang-Hao Chen, Rui Ling, Qing Yao, Ling Wang, Zhong Ma, Department of Vascular and Endocrine Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, Shaanxi Province, China Yu Li, Department of Cell Biology, Fourth Military Medical University, Xi'an 710033, Shaanxi Province, China;Treatment of hepatoma with liposome-encapsulated adriamycin administered into hepatic artery of rats[J];World Journal of Gastroenterology;2006-29
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved