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《Chinese Journal of Blood Transfusion》 2003-05
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Quantitative Detection of HIV-1 RNA for 661 Anti-HIV-1 Sero-positive Plasma

Ma Yicai,Chen Lirong,Alison Cox* School of Life Science and Technology,University of Electronic Science and Technology of China,Chengdu 610054,China  
Objective To assess the plasma HIV-1 RNA level of HIV-infected persons and AIDS patients.Methods The HIV-1 RNA concentrations of 661 anti-HIV-1 sero-positive specimens from HIV-infected persons and AIDS patients were tested by NUCLISENSTM HIV-1 QT.Results Among 661 specimens,the HIV-1 RNA concentrations in 469 plasma (70.95%) were determined,and with the concentration distributions of 2.98% (≤500 cp/ml),20.90%[(501-3000) cp/ml],17.07%[(3001-10000)cp/ml],14.29%[(10001-30000)cp/ml],44.13% (30000 cp/ml),respectively.Whereas the HIV-1 RNA concentrations in 192 plasma (29.05%) were under the detection limit value of the method in the test.Conclusion Most of 469 HIV-infected persons and AIDS patients have a high HIV-1 RNA level.
【CateGory Index】: R446.5
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