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《Chinese Journal of Blood Transfusion》 2007-01
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A study of HLA-B~*27 subtypes and their association with ankylosing spondylitis

CHEN Changrong, ZHANG Zhongying, NI Hongying, et al. Xiamen Blood Center, Xiamen 361004 China  
Objective To compare the frequencies of HLA-B*27 genetic subtypes in AS patients with those of unrelated Fujian donors from Chinese Marrow Donor Program. The association of AS with HLA-B*27 genetic subtypes was also investigated. Methods HLA-B*27 gene and genetic subtypes were determined by PCR-SSO and PCR-SSP methods. Results In unrelated donors group we found 7 subtypes of HLA-B*27 gene, that were B*2703、B*2704、B*2705、B*2706、B*2707、B*2711、B*2720. And alleles of B*2704、B*2705、B*2707、B*2711、B*2715 were found in AS patients. The HLA-B*27 genetic subtype frequencies of the two groups were not found statistical difference(P0.05). Conclusion The polymorphism distribution of HLA-B*27 genetic subtypes between unrelated donors and AS patients might have no significant difference.
【Fund】: 福建省卫生厅青年科研课题(编号:2004-1-29)
【CateGory Index】: R593.23
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【References】
Chinese Journal Full-text Database 2 Hits
1 Pan Ke-nv1,Yang Wen-bo2,Tan Deng-ling2 (1.The Frist People′s Hospital of Hangzhou,Hangzhou 310006,China;2.Hangzhou D.A.Medical Laboratory,Hangzhou 310000,China);Establishment of HLA-B27 polymerase chain reaction system and its initial clinical application[J];Chinese Journal of Health Laboratory Technology;2008-06
2 XU Wei-hua1,FU Sheng-miao2,ZHAO Ying2 . (1. Hainan University,Haikou,Hainan 570228,China. 2. Center Laboratory,People′s Hospital of Hainan Provincial,Haikou,Hainan 570311,China );The study between the gene and the subtypes of HLA-B27 and ankylosing spondylitis in Hainan[J];Chinese Journal of Birth Health & Heredity;2008-06
【Co-citations】
Chinese Journal Full-text Database 3 Hits
1 LI Wei1 HUANG Xia2(1Chongqing Blood Center,Chongqing,400015,China;2Department of Epidemiology,the Third Military University,Chongqing);Study on association between HLA-B27 allele subtypes and ankylosing spondylitis[J];Journal of Clinical Hematology (Blood Transfusion & Laboratory Medicine Edition);2007-05
2 TANG Qiu-ping, YANG Xiang-ping, ZHAO Jian-li, et al.(Hainan Blood Center, Hainan 570311, China);STUDY ON THE APPLICATION OF PCR-SSP TECHNIQUE IN THE HLA-A,B,DRB1 GENE POLYMORPHISM IN HAN PEOPLE OF HAINAN[J];Modern Preventive Medicine;2008-20
3 XU Wei-hua1,FU Sheng-miao2,ZHAO Ying2(1.Institute of Tropical Bioscience,Chinese Academy of Tropical Agriculture Sciences,Haikou,Hainan 570311,China.2.Center Laboratory,Hainan Provincial People′s Hospital,Haikou,Hainan 570311,China);Advance in the relation of the alleles and subtypes of the HLA-B27 and AS[J];Chinese Journal of Birth Health & Heredity;2007-09
【Co-references】
Chinese Journal Full-text Database 5 Hits
1 HAN Jun-yan,XIONG Ping,YAN Peng;Determination of HLA-B27 subtypes in patients with ankylosing spondylitis by PCR-SSP[J];Acta Academiae Medicinae Militaris Tertiae;2003-15
2 CAI Qing ,HAN Xing hai,CHEN Rui wen,YANG Bo,ZHAO Fu tao. Department of Rheumatology and Immunology,Changhai Hospital,Second Military Medical University,Shanghai 200433,China;Familial aggregation of ankylosing spondylitis[J];Chinese Journal of Rheumatology;2003-11
3 ZENG Xian-guo(Department of Internal Medicine,Railroad Hospital Nanning,Guang Xi,Nanning,530001,China);The causes of death in ankylosing spondylitis:a report of 20 cases[J];Hainan Medical Journal;2006-02
4 Lin Lin,Xin-Gen Zhang,Ya-Qin Liu,Department of Immunogenetics,Beijing Institute of Pediatric,Beijing Children's Hospital,Beijing 100045,China Feng-Qi Wu,Jiang Wang,Department of Internal Medicine,Beijing Children's Hospital,Beijing 100045,China;Differential diagnosis of juvenile ankylosing spondylitis and juvenile rheumatoid arthritis by subtypes of HLA-B27 alleles[J];Chinese Journal of Clinical Rehabilitation;2004-09
5 Feng Hua Liu1,Xiao Chen Hu2,Jiang Bin Wang3,1Department of Blood Transfusion, 2Sickroom of Integrated Chinese and Western Medicine, 3Department of General Surgery,the First Clinical Medical College of Harbin Medical University, Harbin 150001,Heilongjiang Province,China;Polymorphism of virulence gene of ankylosing spondylitis in Han nationality[J];Chinese Journal of Clinical Rehabilitation;2004-17
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 PEI Zi-feng,LI Yan,MA Wei,XU Fei(Department of Anatomy,Dalian Medical University,Dalian 116044,China);Research advancement of correlation between essential hypertension and genetic polymorphism of HLA[J];Journal of Dalian Medical University;2009-03
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 Arthritis Clinic & Research Center,People’s Hospital Lin Jianhao,LUHoushan,et al;ANKYLOSING SPONDYLITIS AND HLA-B27 SUBTYPES: ADISEASE-RELATED RESEARCH INCHINESEHAN NATIONALITY[J];JOURNAL OF BEIJING MEDICAL UNIVERSITY;1994-05
2 FENG Ming-liang, LU Qiong, MA Jun, JI Yue-hua, JI Yun, ZHANG Gong-liang, YANG Ying ( Shanghai Blood Cen-ter, Shanghai 200051 ); CHEN Shu-xian ( Ruijing Hospital, Shanghai Second Medical University, Shanghai 200025);Investigation on the HLA Polymorphism of North China Population in Shanghai Bone Marrow Bank[J];Shanghai J.of Immunology;2002-04
3 DAI Yun-Peng,YAN Wen-Ying①,SHEN Bai-Jun et al.Pediatric Department,Qilu Hospital,Shandong University,Jinan 250012,China.①Shandong Umbilical Cord Blood Bank,Jinan 250012,China[;The polymorphism study of HLA-DRB1 alleles in patients with acute lymphoblasti leukemia[J];Chinese Journal of Immunology;2003-05
4 Jiang Lihua,Fan Lian,Yang Jueqin et al.Shanghai Second Medical University,Shanghai Institute of Immunology,Shanghai 200025;STUDY ON ANKYLOSING SPONDYLITIS AND HLAB27 ALLELES[J];CHINESE JOURNAL OF IMMUNOLOGY;1997-06
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