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《Chinese Journal of Blood Transfusion》 2014-01
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Investigation of cryoprecipitate preparation using automated blood component separator

WANG Fei;WANG Ying;LI Yiming;CHEN Liting;CHEN Baoxin;Blood Center of Shenzhen;  
Objective Cryoprecipitate were made using fully automated blood component separator [SEPAMATIC-SL(Ⅲ) ].The quality of cryoprecipitate was investigated to meet the national quality standard.Meanwhile,the processing of cryoprecipitate preparation was able to be retrospected.Methods 96 units of fresh frozen plasma were randomly divided into two groups.Cryoprecipitate was prepared in a traditional manual method for one group(called manual group) and cryoprecipitate was made using fully automated blood component separator(called machine group) for another group.Cryoprecipitate Ⅷ factor and fibrinogen were tested for each product.Results The levels of cryoprecipitate Ⅷ factor were(101.1 ± 25.4) IU and(102.5 ± 20.6) IU individually for manual group and machine group.The differences were of no statistical significance(n = 48,t = 0.178,P 0.05).The qualified product rates were 60.42% and 100% for manual and machine group respectively.The differences were of statistical significance(n = 48,χ2= 20.463a,P 0.05).The levels of fibrinogen were(220.6 ± 69.3) mg and(264.8 ± 70.5) mg for manual group and machine group respectively.The qualified product rates were 83.33% and 100% respectively.The differences were of statistical significance(n = 48,χ2= 8.727a,P 0.05).Conclusion Cryoprecipitate was of better quality prepared by machine than made manually.Cryoprecipitate was of higher quality product rate as well.Furthermore,the whole preparation process could be computerized.
【CateGory Index】: R457.1
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【Co-citations】
Chinese Journal Full-text Database 10 Hits
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