Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Blood Transfusion》 2014-04
Add to Favorite Get Latest Update

A follow-up study on one round ELISA reactive donors in Nanning

PANG Dong;SHEN Weidong;ZHENG Hui;QIU Changwen;SU Wujin;LIANG Yian;CHEN Yue;HUANG Jinhuan;NONG Yuan;Central Blood Station in Nanning;  
Objective To evaluate the one round ELISA screening reactive blood donors who is truly infected;and to make suggestions for blood donor calling back strategies.Methods After deferral for 6 months because of ELISA screening reactive,the donors were call back for sampling again with following 3 balance tests:dual ELISA screening,nucleic acid testing(NAT) and related confirmatory test.Results Among 119 cases of blood donors tracking,a) 1 sample was ELISA positive for double reagents and 15 samples were positive for single reagent;b) 1 sample was positive for NAT detection;c) HBsAg neutralization test were all negative;1 sample was positive for anti-HCV restructuring immune imprinted test(RIBA),and inconclusive for 2;anti-HIV western blot(WB) test were all negative;TP antibodies against Treponema pallidum(TPPA) tests were negative.Conclusion The most initial one round ELISA reactive blood donors are false positive,which indicates that plenty of the deferred donors are potentially suitable for donation.Our present policies for blood screening and deferral strategies are worth further consideration.Thus,we suggest to amending some supplements to the policy with adding confirmatory test in routine screening and implementing the calling back criteria for blood donors,so as to reduce the donor lost and ensure the blood safety.
【Fund】: 广西壮族自治区卫生厅科研课题(Z2013729)
【CateGory Index】: R446.6
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 2 Hits
1 REN Furong1,WANG Jingxing2,ZHAO Haiyan1,NESS Paul3,SHAN Hua3,et al.1.Beijing Red Cross Blood Center,Beijing 10088,China;2.Institute of Blood Transfusion,Chinese Academy of Medical Sciences;3.Johns Hopkins Medical Institution,USA;Nucleic acid testing of human immunodeficiency virus and hepatitis C virus among blood donors from five cities of China: estimation of residual transfusion risk[J];Chinese Journal of Blood Transfusion;2007-06
2 YU Hui,XU Qiang,JIN Yan-yan(Hanzhong Municipal Central Blood Station,Hanzhong,Shanxi 723000,China);Discussion on going and retaining of HIV false positive blood donors among unpaid blood donors[J];Laboratory Medicine and Clinic;2012-20
Chinese Journal Full-text Database 10 Hits
1 LIU Lidong,LI Chao,GAO Yu,et al.Shanghai Blood Center,Shanghai 200051,China;Primary research of the importance of ALT testing on the safety of blood donor screening system[J];Chinese Journal of Blood Transfusion;2009-07
2 YE Xian-lin,LI Huo,XU Xiaoxuan,et al.Shenzhen Blood Center,Shenzhen,Guangdong 518035,China;Application on nucleic acid amplification technigues in blood screening for HBV DNA,HCV RNA/HIV-1 RNA[J];Chinese Journal of Blood Transfusion;2010-01
3 NI Hongying,OU Shanhai,XIE Jinzhen,XIE Jinzhen,LIN Yongcai,CHEN Changyrong.OU Shanhai.Xiamen Blood Service,Xiamen 361004,China;Study of occult hepatitis B virus infection among blood donors by different NAT methods[J];Chinese Journal of Blood Transfusion;2011-12
4 NI Hongying,OU Shanhai,XIE Jinzhen,CHEN Changrong.Xiamen Blood Center,Xiamen 361004,China;Application of single specimen nucleic acid test in donor blood screening[J];Chinese Journal of Blood Transfusion;2012-12
5 Li Xinjian(Anyang Central Blood Station,Anyang,Henan 455000,China);The application of nucleic acid testing in keeping blood donor[J];International Journal of Laboratory Medicine;2013-10
6 SONG Mei-lan,REN Fu-rong,GONG Xiao-yan,et al(Beijing Red Cross Blood Center,Beijing 100088);Evaluation on the false positive rate of unqualified donors with positive HBsAg and anti-HCV ELISA screen test[J];Beijing Medical Journal;2013-05
7 CEN Xian-ming Quality Management Department of Central Blood Station of Wuzhou City,Wuzhou 543002,China;Survey of the infection status of volunteer blood donors confirmed with positive HIV in Wuzhou city[J];Acta Medicinae Sinica;2013-01
8 ZHAO Xin;WANG Huan;LI Maosheng;LI Ying;GAO Jialiang;LI Wen;Chengdu Blood Center;;Application of real-time fluorimetry polymerase chain reaction to blood screening in Chengdu[J];Chinese Journal of Blood Transfusion;2014-01
9 LU Huaxin;CHEN Guoan;YAO Li;XIANG Zhengguo;Wuhan Blood Center;;Cost benefit analysis of 43714 donors blood nucleic acid testing applied to screening in Wuhan,China[J];Chinese Journal of Blood Transfusion;2014-02
10 CHENG Weifang;ZHOU Xueyong;DUAN Youhong;LIU Zhong;AnHui Blood Center;Institute of Blood Transfusion,Chinese Academy of Medical Sciences;;Analysis of ELISA and NAT testing between first-time donors and repeated donors[J];Chinese Journal of Blood Transfusion;2014-04
【Secondary Citations】
Chinese Journal Full-text Database 8 Hits
1 Gao Feng,Zhang Xi,Wang Xun,et al.Shanghai Blood Center,Shanghai 200051,China;Investigation on the Mode of Double Testing of Blood for Virus Markers[J];Chinese Journal of Blood Transfusion;2001-04
2 Wang Xun,Zheng Lan,Zhang Xi,et al. Shanghai Blood Center, Shanghai 200051, China;Preliminary experiences of nucleic acid testing in blood screening in Shanghai[J];Chinese Journal of Blood Transfusion;2003-03
3 SUN Ainong, SUI Luhuai, ZHA Yong, et al. Blood Center of Red Cross in Zhongshan , Zhougshan,528403, China;HCV-RNA testing of 28098 blood donors and follow up of some positive cases[J];Chinese Journal of Blood Transfusion;2005-02
4 WANG Lianghua,YE Xianlin,SHANG Guifang,et al.Shenzhen Blood Center,Shenzhen 518035,China;NAT testing for HBV,HCV,HIV on donors' samples negative by ELISA tests[J];Chinese Journal of Blood Transfusion;2005-04
5 LIU Yu-ning,WU Xiao-fei,JIA Yao,et al.Fengxian Blood Bank,Shanghai 201400;The Study on the Confirmatory Protocol of the Reactive Results of Hepatitis B Viral Surface Antigen Blood Screening Test[J];Journal of Clinical Transfusion and Laboratory Medicine;2011-04
6 WANG Xun,JIA Yao,WU Xiao-fei,LIU Xiao-ying(Shanghai Blood Center,Shanghai 200051,China);The analysis on the results of blood screening tests in blood bank[J];Journal of Microbes and Infection;2008-03
7 LIU Chang-Li*,REN Fu-Rong1, L Qiu-Shuang1, LIU Jing-Han, ZHUANG Hui2 Department of Blood Transfusion, General Hospital of PLA, Beijing 100853, China; 1Beijing Red Cross Blood Center,Beijing 100088,China; 2Department of Pathogenic Biology, Peking University Health Science Center, Beijing 100083, China;Stability of Hepatitis C Virus RNA in Various Processing and Storage Conditions[J];Journal of Experimental Hematology;2006-06
8 Kang Laiyi, Sun Yongde, Hao Lianjie, et al. Shanghai Hygiene and Antiepidemic Center Shanghai 200031;Studies on epidemiology of the population with HCV and HEV infections and their epidemic factors in China[J];CHINESE JOURNAL OF INFECTIOUS DISEASES;1997-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved