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《Chinese Journal of Blood Transfusion》 2014-04
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Retrospective analysis and coping measures of poor deaggregation of in vitro apheresis platelets

NIU Changlin;DONG Jinying;ZHANG Meiping;Blood Center of Puyang;  
Objective To investigate the causes of poor deaggregation of in vitro apheresis platelets and its coping measures,to ensure the normal physiological activity of platelets and the clinical infusion effect.Methods During March 2011 to February 2013,poor deaggregation of in vitro apheresis platelets was statistical analyzed.The effect of adding a proper amount of anticoagulants into platelet products on deaggregation was analyzed.Results Poor deaggregation of apheresis platelets appeared in 38 donors,including 2 repeat donors who had poor deaggregation in each donation,more than 20 repeat donors who had one poor deaggregation and 16 first time donors.Adding a proper amount of anticoagulant could effectively improve deaggregation.Conclusion Poor deaggregation of apheresis platelet can occur in the first time donors and repeat donors.Factors related to donors account for the highest proportion of factors associated with poor deaggregation.Targeted measures can effectively reduce the occurrence of poor deaggregation.When platelet poor deaggregation happens,adding a proper amount of anticoagulant can promptly improve it and ensure the clinical effect of platelet.
【CateGory Index】: R457.1
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【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 Ji Fengtao,Liang Jiangjun,Cao minghui,Miao Liping,Wu Qiang,Wang Zhi,Li Jue.Department of Anesthesiology,The Second Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510120;Effects of ulinastatin on activated leukocytes and platelets during intraoperative autotransfusion[J];Lingnan Modern Clinics in Surgery;2010-02
2 FU Liqiang1,SANG Lieyong1,TONG Haiming2.(1.The Blood Center of Shaoxing,Zhejiang Shaoxing 312000,China;2.Department of Clinical Laboratory,Shaoxing People′s Hospital,Zhejiang Shaoxing 312000,China);The comparison and analysis of the apheresis platelet count results with different blood analyzers[J];Laboratory Medicine;2010-10
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4 LI Mei-na;TENG Qing;LIU Kai-mei;LIANG Yan-mei;HUANG Jian-hua;Guangzhou Blood Center;;The critical control point of apheresis platelets by Trima Accel[J];China Modern Medicine;2013-26
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Chinese Journal Full-text Database 4 Hits
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