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《Chinese Journal of Blood Transfusion》 2014-06
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Quantitative analysis of the Rh membrane protein complex in rare Rh deletion type D--individual and family members

ZHANG Xiuzheng;ZHANG Wei;WANG Shouyan;WANG Jing;Binzhou Blood Center;  
Objective To investigate the changes of Rh membrane protein complex of a family which has a rare Rh deletion D- type. Methods Flow Cytometry was used to determine the expression level of RhD,Band3,CD47,GPA,LW and RhAG protein on red blood cells. Results The radio of the protein mentioned above among the whole family( proband,father,mother,daughter and husband) was as follows: 2. 38,1. 61,1. 83,2. 00,0. 62; 1. 03,0. 72,1. 12,0. 85,0. 99,0. 35,0.79,0. 66,0. 88,0. 91,0. 86,0. 80,0. 91,0. 81,0. 87; 2. 46,not available,2. 36,2. 30,1. 12; 0. 70,0. 78,0. 93,0. 86,0. 97.Conclusion The expression of LW was positively related to that of RhD in the studyed family. The CD47 was reduced in the D- individual while other proteins had little change.
【CateGory Index】: R457.11
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【Co-citations】
Chinese Journal Full-text Database 6 Hits
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5 SU Yu-Qing, YU Qiong, LIU Xu1, LIANG Yan-Lian, WEI Tian-Li Shenzhen Blood Center, Shenzhen 518035, Guangdong Province, China; 1Dalian Medical University, Dalian 116023, Liaoning Pro-vince, China;Polymorphism of LW Blood Group Gene in Chinese Population[J];Journal of Experimental Hematology;2008-03
6 YU Qiong,SU Yu-qing,DENG Zhi-hui,et al.Shenzhen Blood Center,Guangdong 518035,China;Association Study between Diabetic Retinopathy and Gene Polymorphisms of Lutheran Glycoproteins,a Cellular Adhesion Molecule[J];Chinese Journal of Prevention and Control of Chronic Diseases;2011-02
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