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《Chinese Journal of Blood Transfusion》 2014-06
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Quantitative analysis of the Rh membrane protein complex in rare Rh deletion type D--individual and family members

ZHANG Xiuzheng;ZHANG Wei;WANG Shouyan;WANG Jing;Binzhou Blood Center;  
Objective To investigate the changes of Rh membrane protein complex of a family which has a rare Rh deletion D- type. Methods Flow Cytometry was used to determine the expression level of RhD,Band3,CD47,GPA,LW and RhAG protein on red blood cells. Results The radio of the protein mentioned above among the whole family( proband,father,mother,daughter and husband) was as follows: 2. 38,1. 61,1. 83,2. 00,0. 62; 1. 03,0. 72,1. 12,0. 85,0. 99,0. 35,0.79,0. 66,0. 88,0. 91,0. 86,0. 80,0. 91,0. 81,0. 87; 2. 46,not available,2. 36,2. 30,1. 12; 0. 70,0. 78,0. 93,0. 86,0. 97.Conclusion The expression of LW was positively related to that of RhD in the studyed family. The CD47 was reduced in the D- individual while other proteins had little change.
【CateGory Index】: R457.11
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