Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Blood Transfusion》 2016-01
Add to Favorite Get Latest Update

Analysis on the levels of TGF-β1 in serum of blood donors with occult HBV infection

LI Jin;JING Yuanyuan;GUO Yan;Shaanxi Blood Center;  
Objective To explore the level of cytokines TGF-β1 and its function in serum of occult HBV infected donors in Xi'an. Methods Blood samples from 40 healthy controls,38 HBV donors and 78 OBI donors were collected. The levels of TGF-β1 were detected by ELISA. The correlation between level of TGF-β1 and ALT or the five HBV serological markers were analyzed. Results Compared with the healthy controls,OBI donors had significantly higher levels of TGF-β1( F = 4. 311,P = 0. 047). The level of TGF-β1 has no significant difference between donors with ALT≤20 U/L and 20 U/L ALT≤40 U / L( t = 2. 266,P = 0. 287). There was no correlation between the level of TGF-β1 and the five HBV markers. Conclusion There may be association between the level of TGF-β1 and the pathogenesis of OBI. The level of TGF-β1may have no correlation with the level of liver inflammation and the five HBV serological markers.
【Fund】: 陕西省自然科学基金(2013JQ4041)
【CateGory Index】: R512.62
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved