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《Chinese Journal of Blood Transfusion》 2016-04
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Distribution and relative influential factors of unexpected antibody for cancer patients

LI Xiying;ZHAO Guohua;ZHAO Weiqi;TANG Dabin;PENG Tao;LIU Min;ZHOU Dongyan;Department of Blood Transfusion,Cancer Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;  
Objective To investigate the distribution and associated factors of unexpected antibody in cancer patients.Methods CAT( column agglutination technique) had been used to screen unexpected antibody of 48 369 cancer patients in our hospital from January 2011 to October 2015,according to the 2010 version of AABB guidelines for antibody identification. Results Unexpected antibody has been found in 255 patients at a total rate of 0. 53%. anti-M antibody occurred most( 57 /22. 35%),followed by anti-Lea antibody( 54 /21. 18%) and anti-E antibody( 53 /20. 78%) and other uncommon unexpected antibody,which was associated with colorectal cancer,lymphoma,metastasis,blood transfusion history,gender,pregnancies and labors and Rh blood group based on multivariable Logistic regression analysis. Conclusion The generation of unexpected antibody of cancer patients is influenced by many factors,such as diseases,transfusion history,gender,etc.Regular screening of Rh and MNS blood group based on the distribution of unexpected antibody may meet cancer patients' demand for blood transfusion and guarantee the safety and effectiveness of clinical blood transfusion.
【CateGory Index】: R730.43
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 XU Xianghua;Jiangsu Taizhou Blood Center;;Irregular antibody screening results of 22682 volunteer blood donors[J];中国输血杂志;2015-09
【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 LI Xiying;ZHAO Guohua;ZHAO Weiqi;TANG Dabin;PENG Tao;LIU Min;ZHOU Dongyan;Department of Blood Transfusion,Cancer Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;;Distribution and relative influential factors of unexpected antibody for cancer patients[J];中国输血杂志;2016-04
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 WANG Shuping;TANG Weixian;CHEN Huife;LI Zhiqiang;Department of Laboratory,ShanghaiFirst Maternity and Infant Hospital,Tongji University,School of Medicine;Blood Transfusion Department of the Sixth People's Hospital,Shanghai Jiaotong University;;Research of the clinical value about irregular antibody screening of 22481 pregnant women[J];中国输血杂志;2014-02
2 Fan Daowang, Sun Yun, Miao Tianhong, et al (Beijing Red Cross Blood Center, Beijing, 100088);Analysis of 101 irregular antibodies distribution[J];北京医学;2005-10
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