Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Blood Transfusion》 2018-03
Add to Favorite Get Latest Update

Analysis and evaluation of correlative factors of high perioperative blood transfusion demand for patients with intrathoracic digestive tract tumor

ZENG Qingpeng;LI Jiagen;XUE Qi;HUANG Jinfeng;ZHANG Liangze;GAO Shu-geng;ZHAO Jun;Department of Thoracic Surgery,National Cancer Center/Cancer Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College;  
Objective To understand the causes of high perioperative blood transfusion demand in patients with esophageal and cardiac cancer,and to analyze the influence of high blood transfusion demand on postoperative recovery and the changes of related biochemical indexes. Methods Esophageal and cardiac cancer Patients ' clinical data( Oct,2012-Oct,2017) was collected in the Department of Thoracic Surgery,Cancer Hospital,Chinese Academy of Medical Sciences were collected. A total of 27 cases with red blood cell( RBC) transfusion volumes ≥5 U were defined as the high transfusion demand group. Another 27 cases were selected from the rest of the patients as the control group. By comparing the clinical characteristics between two groups,the influencing factors of high blood transfusion demand and the influence of high transfusion demand on postoperative recovery were analyzed.Results A total of 6448 patients with esophageal and cardiac cancer underwent surgery in our department from October 2012 to October2017 and the high blood transfusion demand rate was 0. 42%( 27/6 448).( 1) The ratio of patients with preoperative comorbidities was 66. 67%( 18/27) in the high demand transfusion group versus 37. 04%( 10/27) in the control group( P0. 05),and the ratio of patients with anemia was 48. 15%( 13/27)versus 22. 22%( 6/27)( P0. 05).( 2) The ratio of high blood transfusion demand caused by postoperative delayed bleeding and intraoperative bleeding was 62. 96%( 17/27) vs 33. 33%( 9/27)( P0. 05),respectively.( 3) The incidence of complications was 62. 96%( 17/27) in the high transfusion demand group versus 33. 33%( 9/27) in the control group( P0. 05),and the length of hospitalization( d) and ICU stay( d) were( 24. 70 ± 17. 60) vs( 21. 41 ± 8. 16)( P 0. 05),( 1. 12±2. 01) vs( 0. 37±1. 36)( P0. 05),respectively.( 4) The platelet count( Plt),K+and Ca2+levels( mmol/L) of pre-and post-transfusion in the high transfusion demand group were( 235. 59±76. 44) versus( 159. 81±87. 80)( P0. 05),( 4. 18±0. 39) versus( 3. 94±0. 47),( P0. 05),( 2. 35±0. 43) versus( 1. 90±0. 29)( P0. 05) respectively. The control group were correspondingly( 225. 89±62. 47 vs( 190. 59±61. 15)( P0. 05),( 4. 21±0. 36) vs( 4. 17±0. 43)( P0. 05),( 2. 28±0. 19) vs( 2. 02±0. 14)( P0. 05).Conclusion Preoperative comorbidity and anemia were the significant risk factors of high perioperative blood transfusion demand for esophageal and cardiac cancer patients. High perioperative blood transfusion demand is mainly caused by postoperative bleeding. It increases postoperative complication rate and deregulates coagulative function and electrolyte levels.
【CateGory Index】: R457.1;R735
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved